A
Ariella Glasner
Researcher at Hebrew University of Jerusalem
Publications - 35
Citations - 2145
Ariella Glasner is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Receptor & Immune system. The author has an hindex of 20, co-authored 33 publications receiving 1813 citations. Previous affiliations of Ariella Glasner include Tel Aviv University.
Papers
More filters
Journal ArticleDOI
NK cells link obesity-induced adipose stress to inflammation and insulin resistance
Felix M. Wensveen,Vedrana Jelenčić,Sonja Valentić,Marko Šestan,Tamara Turk Wensveen,Sebastian Theurich,Ariella Glasner,Davor Mendrila,Davor Štimac,F. Thomas Wunderlich,Jens C. Brüning,Ofer Mandelboim,Bojan Polić +12 more
TL;DR: Deficiency of NK cells, NCR1 or IFN-γ prevented the accumulation of proinflammatory macrophages in VAT and greatly ameliorated insulin sensitivity, and NK cells are key regulators of macrophage polarization and insulin resistance in response to obesity-induced adipocyte stress.
Journal ArticleDOI
Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR
Noa Stanietsky,Tihana Lenac Rovis,Ariella Glasner,Einat Seidel,Pinchas Tsukerman,Rachel Yamin,Jonatan Enk,Stipan Jonjić,Ofer Mandelboim +8 more
TL;DR: It is shown that TIGIT is a powerful inhibitory receptor for mouse NK cells and binds to mPVR with higher affinity than the co‐stimulatory PVR‐binding receptor mouse DNAM1 (mDNAM1).
Journal ArticleDOI
Improving Survival Rates in Two Models of Spontaneous Postoperative Metastasis in Mice by Combined Administration of a β-Adrenergic Antagonist and a Cyclooxygenase-2 Inhibitor
Ariella Glasner,Roi Avraham,Roi Avraham,Ella Rosenne,Marganit Benish,Oded Zmora,Oded Zmora,Shaily Shemer,Hadas Meiboom,Shamgar Ben-Eliyahu +9 more
TL;DR: Overall, propranolol and etodolac administration, which could be applied perioperatively in most cancer patients with minimal risk and low cost, has counteracted several immunologic and endocrinologic perturbations and improved recurrence-free survival rates in mice undergoing primary tumor excision.
Journal ArticleDOI
Recognition and Prevention of Tumor Metastasis by the NK Receptor NKp46/NCR1
Ariella Glasner,Hormas Ghadially,Chamutal Gur,Noa Stanietsky,Pinchas Tsukerman,Jonatan Enk,Ofer Mandelboim +6 more
TL;DR: In vivo, in this study, it is shown in vivo that NKp46/NCR1 plays an important role in controlling B16 and D122 metastasis, the first evidence for the direct involvement of a specific NK killer receptor in preventing tumor metastasis.
Journal ArticleDOI
NKp46 Receptor-Mediated Interferon-γ Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis
Ariella Glasner,Assi Levi,Jonatan Enk,Batya Isaacson,Sergey Viukov,Shari Orlanski,Alon Scope,Tzahi Neuman,Claes D. Enk,Jacob H. Hanna,Veronika Sexl,Stipan Jonjić,Barbara Seliger,Laurence Zitvogel,Ofer Mandelboim +14 more
TL;DR: It is shown that NK cells prevent tumor metastases in vivo by editing tumor architecture via NKp46‐mediated IFN‐&ggr; production that leads to upregulation of extracellular matrix protein FN1 in the tumor.