A
Armand Valsesia
Researcher at Nestlé
Publications - 75
Citations - 12031
Armand Valsesia is an academic researcher from Nestlé. The author has contributed to research in topics: Weight loss & Genome-wide association study. The author has an hindex of 24, co-authored 73 publications receiving 11138 citations. Previous affiliations of Armand Valsesia include Swiss Institute of Bioinformatics & Wellcome Trust Sanger Institute.
Papers
More filters
Journal ArticleDOI
GH deficiency status combined with GH receptor polymorphism affects response to GH in children.
Armand Valsesia,Pierre Chatelain,Adam Stevens,Valentina A Peterkova,Alicia Belgorosky,Mohamad Maghnie,Franco Antoniazzi,Ekaterina Koledova,Jérôme Wojcik,Pierre Jacques Farmer,Benoit Destenaves,Peter E. Clayton +11 more
TL;DR: Responses to r-hGH depend on the interaction between GHD severity and GHRd3 carriage, and GE profiles were significantly different between the groups, indicating that the interactions between GH status and G HRd3riage can be identified at a transcriptomic level.
Journal ArticleDOI
Rational and design of an overfeeding protocol in constitutional thinness: Understanding the physiology, metabolism and genetic background of resistance to weight gain.
Yiin Ling,Bogdan Galusca,Jörg Hager,Léonard Féasson,Armand Valsesia,Jacques Epelbaum,Virginie Alexandre,Emma Wynn,Cécile Dinet,Radu Palaghiu,Michel Peoc'h,Yves Boirie,Christophe Montaurier,Bruno Estour,Natacha Germain +14 more
TL;DR: The findings could possibly open to therapeutic approaches to help CT patients to gain weight as well as provide a better understanding of energy regulation with regard to treat obesity (resistance to weight loss), a mirror image of CT.
Journal ArticleDOI
Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance
Alice Matone,Marie-Pier Scott-Boyer,Jérôme Carayol,Parastoo Fazelzadeh,Gregory Lefebvre,Armand Valsesia,Celine Charon,Jacques Vervoort,Arne Astrup,Wim H. M. Saris,Melissa J. Morine,Jörg Hager +11 more
TL;DR: Gene expression in the adipose tissue showed that CPS1 expression levels were associated with successful weight maintenance and with several SNPs within CPS1, suggesting that it might be partly genetically determined in humans.
Journal ArticleDOI
Salivary α-amylase copy number is not associated with weight trajectories and glycemic improvements following clinical weight loss: results from a 2-phase dietary intervention study
Armand Valsesia,Sameer S. Kulkarni,Julien Marquis,Patricia Leone,Polina Mironova,Ondine Walter,M. F. Hjorth,Patrick Descombes,Jörg Hager,Wim H. M. Saris,Arne Astrup,Christian Darimont,Nathan J O'Callaghan,Nathan J O'Callaghan +13 more
TL;DR: In the absence of association with weight trajectories or glycemic improvements, the AMY1 CN cannot be considered as an important biomarker for response to a clinical weight loss and weight maintenance programs in overweight/obese subjects.
Journal ArticleDOI
FADS1 genotype is distinguished by human subcutaneous adipose tissue fatty acids, but not inflammatory gene expression
Shannon L. Klingel,Armand Valsesia,Arne Astrup,Marie Kunešová,Wim H. M. Saris,Dominique Langin,Dominique Langin,Dominique Langin,Nathalie Viguerie,Nathalie Viguerie,David M. Mutch +10 more
TL;DR: This study showed that FADS1 genotype is distinguished by SAT fatty acid profiles, but not inflammatory gene expression.