J
Jérôme Wojcik
Researcher at Merck Serono
Publications - 60
Citations - 5928
Jérôme Wojcik is an academic researcher from Merck Serono. The author has contributed to research in topics: Proteomics Standards Initiative & Genome-wide association study. The author has an hindex of 26, co-authored 60 publications receiving 5538 citations. Previous affiliations of Jérôme Wojcik include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Journal ArticleDOI
The protein-protein interaction map of Helicobacter pylori.
Jean-Christophe Rain,Luc Selig,Hilde De Reuse,Véronique Battaglia,Céline Reverdy,Stéphane Simon,Gerlinde Lenzen,Fabien Petel,Jérôme Wojcik,Vincent Schächter,Y. Chemama,Agnès Labigne,Pierre Legrain +12 more
TL;DR: A large-scale protein–protein interaction map of the human gastric pathogen Helicobacter pylori is built and the assignment of unannotated proteins to biological pathways is permitted.
Journal ArticleDOI
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data.
Henning Hermjakob,Luisa Montecchi-Palazzi,Gary D. Bader,Jérôme Wojcik,Lukasz Salwinski,Arnaud Ceol,Susan Moore,Sandra Orchard,Ugis Sarkans,Christian von Mering,Bernd Roechert,Sylvain Poux,Eva Jung,Henning Mersch,Paul J. Kersey,Michael Lappe,Yixue Li,Rong Zeng,Debashis Rana,Macha Nikolski,Holger Husi,Christine Brun,K. Shanker,Seth G. N. Grant,Chris Sander,Peer Bork,Weimin Zhu,Akhilesh Pandey,Alvis Brazma,Bernard Jacq,Marc Vidal,David James Sherman,Pierre Legrain,Gianni Cesareni,Ioannis Xenarios,David Eisenberg,Boris Steipe,Christopher W. V. Hogue,Rolf Apweiler +38 more
TL;DR: This work proposes a community standard data model for the representation and exchange of protein interaction data, jointly developed by members of the Proteomics Standards Initiative (PSI) and the Human Proteome Organization (HUPO).
Journal ArticleDOI
Protein interaction mapping: A Drosophila case study
Etienne Formstecher,Sandra Aresta,Vincent Collura,Alexandre Hamburger,Alain Meil,Alexandra Trehin,Céline Reverdy,Virginie Betin,Sophie Maire,Christine Brun,Bernard Jacq,Monique Arpin,Yohanns Bellaïche,Saverio Bellusci,Philippe Benaroch,Michel Bornens,Roland Chanet,Philippe Chavrier,Olivier Delattre,Valérie Doye,Richard G. Fehon,Richard G. Fehon,Gérard Faye,Thierry Galli,Jean-Antoine Girault,Bruno Goud,Jean de Gunzburg,Ludger Johannes,Marie-Pierre Junier,Vincent Mirouse,Ashim Mukherjee,Dora Papadopoulo,Franck Perez,Anne Plessis,Carine Rossé,Simon Saule,Dominique Stoppa-Lyonnet,Alain Vincent,Michael A. White,Pierre Legrain,Jérôme Wojcik,Jacques Camonis,Jacques Camonis,Laurent Daviet +43 more
TL;DR: This work used a high-throughput yeast two-hybrid (Y2H)-based technology to screen 102 bait proteins from Drosophila melanogaster, most of them orthologous to human cancer-related and/or signaling proteins, against high-complexity fly cDNA libraries.
Journal ArticleDOI
Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus
Sergey V. Kozyrev,Anna Karin Abelson,Jérôme Wojcik,Ammar Zaghlool,M.V. Prasad Linga Reddy,Elena Sánchez,Iva Gunnarsson,Elisabet Svenungsson,Gunnar Sturfelt,Andreas Jönsen,Lennart Truedsson,Bernardo A. Pons-Estel,Torsten Witte,Sandra D'Alfonso,Nadia Barrizzone,Maria Giovanna Danieli,Carmen Gutiérrez,Ana Suárez,Peter Junker,Helle Laustrup,María Francisca González-Escribano,Javier Martin,Hadi Abderrahim,Marta E. Alarcón-Riquelme +23 more
TL;DR: The findings implicate BANK1 as a susceptibility gene for SLE, with variants affecting regulatory sites and key functional domains, which could contribute to sustained B cell–receptor signaling and B-cell hyperactivity characteristic of this disease.
Journal ArticleDOI
Functional Proteomics Mapping of a Human Signaling Pathway
Frédéric Colland,Xavier Jacq,Virginie Trouplin,Christelle Mougin,Caroline Groizeleau,Alexandre Hamburger,Alain Meil,Jérôme Wojcik,Pierre Legrain,Jean-Michel Gauthier +9 more
TL;DR: An integrated approach combining large-scale protein interaction mapping, exploration of the interaction network, and cellular functional assays performed on newly identified proteins involved in a human signaling pathway is presented, validating this integrated functional proteomics approach.