A
Arnav Mehta
Researcher at Harvard University
Publications - 67
Citations - 2881
Arnav Mehta is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 16, co-authored 45 publications receiving 1629 citations. Previous affiliations of Arnav Mehta include University of California, Los Angeles & Broad Institute.
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Journal ArticleDOI
MicroRNAs as regulatory elements in immune system logic
Arnav Mehta,David Baltimore +1 more
TL;DR: The mechanisms by which several miRNAs influence immune development and buffer normal haematopoietic output are discussed, first at the level of haematic stem cells, then in innate and adaptive immune cells, and the pathological consequences of dysregulation of these mi RNAs are discussed.
Journal ArticleDOI
Conversion of Danger Signals into Cytokine Signals by Hematopoietic Stem and Progenitor Cells for Regulation of Stress-Induced Hematopoiesis
Jimmy L. Zhao,Chao Ma,Ryan M. O'Connell,Arnav Mehta,Race Diloreto,James R. Heath,David Baltimore +6 more
TL;DR: This study has uncovered an important property of HSPCs that enables them to convert danger signals into versatile cytokine signals for the regulation of stress hematopoiesis.
Journal ArticleDOI
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Aaron J. Grossberg,Linda C. Chu,Christopher R. Deig,Eliot K. Fishman,William L. Hwang,William L. Hwang,William L. Hwang,Anirban Maitra,Daniel L. Marks,Arnav Mehta,Arnav Mehta,Arnav Mehta,Nima Nabavizadeh,Diane M. Simeone,Colin D. Weekes,Charles R. Thomas +15 more
TL;DR: The authors review the current multidisciplinary standards of care in pancreatic cancer with a focus on emerging concepts in Pancreatic cancer detection, precision therapy, and survivorship.
Journal ArticleDOI
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection.
Niyati Desai,Azfar Neyaz,Annamaria Szabolcs,Angela R. Shih,Jonathan H. Chen,Vishal Thapar,Linda T. Nieman,Alexander Solovyov,Arnav Mehta,Arnav Mehta,David J. Lieb,Anupriya S. Kulkarni,Christopher Jaicks,Katherine Xu,Michael J. Raabe,Christopher J. Pinto,Dejan Juric,Ivan Chebib,Robert B. Colvin,Arthur Y. Kim,Robert Monroe,Sarah Warren,Patrick Danaher,Jason Reeves,Jingjing Gong,Erroll H. Rueckert,Benjamin D. Greenbaum,Nir Hacohen,Nir Hacohen,Stephen M. Lagana,Miguel Rivera,Miguel Rivera,Lynette M. Sholl,James R. Stone,David T. Ting,Vikram Deshpande +35 more
TL;DR: Analysis of autopsy specimens from 24 patients who succumbed to SARS-CoV-2 infection is shown using a combination of different RNA and protein analytical platforms to characterize inter-patient and intra-patient heterogeneity of pulmonary virus infection.
Journal ArticleDOI
An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
Mati Mann,Arnav Mehta,Arnav Mehta,Jimmy L. Zhao,Kevin Y. Lee,Georgi K. Marinov,Yvette Garcia-Flores,Li-Fan Lu,Alexander Y. Rudensky,David Baltimore +9 more
TL;DR: A miRNA-based regulatory network that enables precise NF-κB activity in mouse macrophages is described, which enables a robust yet time-limited inflammatory response essential for functional immunity.