P
Patrick Durez
Researcher at Cliniques Universitaires Saint-Luc
Publications - 236
Citations - 10569
Patrick Durez is an academic researcher from Cliniques Universitaires Saint-Luc. The author has contributed to research in topics: Rheumatoid arthritis & Medicine. The author has an hindex of 39, co-authored 197 publications receiving 9355 citations. Previous affiliations of Patrick Durez include Université catholique de Louvain & Russian Academy.
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Journal ArticleDOI
Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force
Josef S Smolen,Ferdinand C. Breedveld,Gerd R Burmester,Vivian P. Bykerk,Maxime Dougados,Paul Emery,Tore K Kvien,M Victoria Navarro-Compán,Susan Oliver,Monika Schoels,Marieke Scholte-Voshaar,Tanja Stamm,Michaela Stoffer,Tsutomu Takeuchi,Daniel Aletaha,Jose Louis Andreu,Martin Aringer,Martin J. Bergman,Neil Betteridge,H. Bijlsma,Harald Burkhardt,Mario H. Cardiel,Bernard Combe,Patrick Durez,João Eurico Fonseca,A. Gibofsky,Juan J. Gomez-Reino,Winfried Graninger,Pekka Hannonen,Boulos Haraoui,Marios Kouloumas,Robert Landewé,Emilio Martín-Mola,Peter Nash,Mikkel Østergaard,Andrew J. K. Östör,Pam Richards,T. Sokka-Isler,Carter Thorne,Athanasios G. Tzioufas,Ronald F van Vollenhoven,Martinus de Wit,Désirée van der Heijde +42 more
TL;DR: The 4 overarching principles and 10 recommendations are based on stronger evidence than before and are supposed to inform patients, rheumatologists and other stakeholders about strategies to reach optimal outcomes of RA.
Journal ArticleDOI
Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
Wolfgang Hueber,Dhavalkumar D. Patel,Thaddeus P. Dryja,Andrew M Wright,Irina Koroleva,Gerard Bruin,Christian Antoni,Zoe Diana Draelos,Michael H. Gold,Patrick Durez,Paul P. Tak,Juan J. Gomez-Reino,C. Stephen Foster,Rosa Y. Kim,C. Michael Samson,Naomi S. Falk,David S. Chu,David Callanan,Quan Dong Nguyen,Kristine Rose,Asifa Haider,Franco Di Padova +21 more
TL;DR: The results demonstrate that IL-17A participates in psoriasis, rheumatoid arthritis, and uveitis and that the antibody against this cytokine may be an effective therapeutic agent, and warrant larger clinical trials to assess further the safety and efficacy of AIN457.
Journal ArticleDOI
Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial
Paul Emery,Ferdinand C. Breedveld,Stephen B. Hall,Patrick Durez,David J. Chang,Deborah Robertson,A. Singh,Ronald Pedersen,Andrew S Koenig,Bruce Freundlich +9 more
TL;DR: Both clinical remission and radiographic non-progression are achievable goals in patients with early severe rheumatoid arthritis within 1 year of combined treatment with etanercept plus methotrexate.
Supplementary Materials for Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
Wolfgang Hueber,Dhavalkumar D. Patel,Thaddeus P. Dryja,Andrew M Wright,Gerard Bruin,Christian Antoni,Michael H. Gold,Patrick Durez,Paul P. Tak,Juan J. Go,C. Stephen Foster,Rosa Y. Kim,C. Michael Samson,Naomi S. Falk,David S. Chu,David Callanan,Asifa Haider +16 more
Journal ArticleDOI
Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept - Twelve-month results of a phase IIb, double-blind, randomized, placebo-controlled trial
Joel M. Kremer,Maxime Dougados,P. Emery,Patrick Durez,Jean Sibilia,William Shergy,Serge Steinfeld,Elizabeth A. Tindall,Jean-Claude Becker,Tracy Li,Isaac Nuamah,Richard Aranda,Larry W. Moreland +12 more
TL;DR: Abatacept was associated with significant reductions in disease activity and improvements in physical function that were maintained over the course of 12 months in patients with RA that had remained active despite methotrexate (MTX) therapy.