A
Astrid M. Roy
Researcher at University Medical Center New Orleans
Publications - 5
Citations - 384
Astrid M. Roy is an academic researcher from University Medical Center New Orleans. The author has contributed to research in topics: Alu element & Genome. The author has an hindex of 5, co-authored 5 publications receiving 362 citations. Previous affiliations of Astrid M. Roy include Tulane University & Louisiana State University.
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Journal ArticleDOI
Potential gene conversion and source genes for recently integrated Alu elements.
Astrid M. Roy,Marion L. Carroll,Son V. Nguyen,Abdel Halim Salem,Michael Oldridge,Andrew O.M. Wilkie,Mark A. Batzer,Prescott L. Deininger +7 more
TL;DR: Analysis of Alu Ya5 elements containing one to four (Ya1-Ya4) of the Ya5 subfamily-specific mutations suggests that gene conversion contributed as much as 10%-20% of the variation between recently integrated Alu elements.
Journal ArticleDOI
Recently integrated human Alu repeats: finding needles in the haystack.
Astrid M. Roy,Marion L. Carroll,David H. Kass,Son V. Nguyen,Abdel Halim Salem,Abdel Halim Salem,Mark A. Batzer,Prescott L. Deininger +7 more
TL;DR: The utility of two complementary methods for rapid detection of newly integrated Alu elements based on an anchor-PCR technique and an Allele-Specific Alu PCR technique are explored by applying them to the identification of members of the smallest previously identified subfamily of Alu repeats in the human genome termed Ya8.
Journal ArticleDOI
Upstream flanking sequences and transcription of SINEs.
Astrid M. Roy,Neva C West,Neva C West,Aravinda Rao,Prateek Adhikari,Claudina Alemán,Claudina Alemán,Anthony P. Barnes,Anthony P. Barnes,Prescott L. Deininger +9 more
TL;DR: This work evaluated the ability of upstream flanking sequences to regulate the transcription of three different SINEs (Alu, B2 and ID) by constructing chimeric constructs with known 5' flanks sequences of RNA polymerase III-transcribed genes and found the 7SL sequence proved most efficient in increasing SINE transcription.
Journal ArticleDOI
cDNAs Derived from Primary and Small Cytoplasmic Alu (scAlu) Transcripts
TL;DR: In this paper, the authors have identified and sequenced twenty-six cDNAs derived from primary Alu transcripts, which are known to belong to different, previously described Alu subfamilies.
Journal ArticleDOI
Recent B2 element insertions in the mouse genome.
TL;DR: The detection of the B2 element only in the BalbC strain suggests that the element recently inserted within this mouse population when the initial laboratory colony was formed, potentially allowing for their identification.