Son V. Nguyen

TL;DR: It is concluded that Indian castes are most likely to be of proto-Asian origin with West Eurasian admixture resulting in rank-related and sex-specific differences in the genetic affinities of castes to Asians and Europeans.

TL;DR: Analysis of mosaic Yb8 elements suggests gene conversion played an important role in generating sequence diversity among these elements, and newly identified Alu insertion polymorphisms will be useful tools for the study of human genomic diversity.

TL;DR: The distribution of ancestral alleles is consistent with an origin of early modern human populations in sub-Saharan Africa, the isolation and preservation of ancestralalleles within Africa, and an expansion out of Africa into Eurasia.

TL;DR: Three previously classified Alu Y elements linked with disease belong to the Yc1 subfamily, supporting the retroposition potential of this subfamily and demonstrating that the AluY subfamily currently has a very low amplification rate in the human genome.

TL;DR: Analysis of Alu Ya5 elements containing one to four (Ya1-Ya4) of the Ya5 subfamily-specific mutations suggests that gene conversion contributed as much as 10%-20% of the variation between recently integrated Alu elements.