T
Tamim H. Shaikh
Researcher at University of Colorado Denver
Publications - 91
Citations - 9914
Tamim H. Shaikh is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Copy-number variation & Low copy repeats. The author has an hindex of 44, co-authored 90 publications receiving 9320 citations. Previous affiliations of Tamim H. Shaikh include Louisiana State University & Children's Hospital of Philadelphia.
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Journal ArticleDOI
The DNA sequence of human chromosome 22
Ian Dunham,Nobuyoshi Shimizu,Bruce A. Roe,S. Chissoe,Adrienne Hunt,Joanna Collins,Richard Bruskiewich,David Beare,Michele Clamp,Luc J. Smink,R Ainscough,J P Almeida,A K Babbage,C L Bagguley,J Bailey,K F Barlow,K Bates,O. Beasley,Christine P. Bird,S. Blakey,Anne Bridgeman,D. Buck,J. Burgess,J. Burgess,W Burrill,John Burton,C Carder,Nigel P. Carter,Yuan Chen,Graeme T Clark,S. M. Clegg,V. Cobley,Charlotte G. Cole,R. E. Collier,R. Connor,D. Conroy,N Corby,G. J. Coville,Antony V. Cox,J. C. Davis,J. C. Davis,Elisabeth Dawson,Pawandeep Dhami,C. Dockree,S. J. Dodsworth,Richard Durbin,Andrew D. Ellington,Kathryn L. Evans,J. M. Fey,K. Fleming,Lisa French,A. A. Garner,James G. R. Gilbert,Melanie E. Goward,Darren Grafham,Mark Griffiths,C. Hall,C. Hall,Rebekah Hall,G. Hall-Tamlyn,R. W. Heathcott,R. W. Heathcott,Shuk-Mei Ho,S. Holmes,Sarah E. Hunt,Matthew Jones,J K Kershaw,A M Kimberley,A. King,Gavin K. Laird,Cordelia Langford,Margaret A. Leversha,Christine Lloyd,D. M. Lloyd,I. D. Martyn,M Mashreghi-Mohammadi,Lucy Matthews,O. T. McCann,Joseph L. McClay,Stuart McLaren,Amanda McMurray,Sarah Milne,B. J. Mortimore,C. Odell,R. Pavitt,A. V. Pearce,D. Pearson,Benjamin Phillimore,Sam Phillips,Robert W. Plumb,H. Ramsay,Y. Ramsey,Lesley J. Rogers,Mark T. Ross,Carol Scott,Harminder Sehra,C. D. Skuce,S. Smalley,Michelle Smith,Carol Soderlund,L. Spragon,Charles A. Steward,John Sulston,R. M. Swann,M. Vaudin,M. Vaudin,Melanie M. Wall,J. M. Wallis,M. N. Whiteley,M. N. Whiteley,Dave Willey,L. Williams,Scott M. Williams,H. Williamson,H. Williamson,T. E. Wilmer,Laurens G. Wilming,Charmain L. Wright,Tim Hubbard,David R. Bentley,Stephan Beck,Jane Rogers,Shinsei Minoshima,Kazuhiko Kawasaki,Takashi Sasaki,Shuichi Asakawa,Jun Kudoh,Ai Shintani,Kazunori Shibuya,Y. Yoshizaki,Noriaki Aoki,Susumu Mitsuyama,Feng Chen,L. Chu,Judy S. Crabtree,Stéphane Deschamps,A. Do,T. Do,Angela Dorman,F. Fang,Y. Fu,P. Hu,Axin Hua,Steve Kenton,Hongshing Lai,H. I. Lao,Jennifer Lewis,S. Lewis,Shaoping Lin,P. Loh,Eda Malaj,T. Nguyen,Huaqin Pan,S. Phan,S. Qi,Y. Qian,L. Ray,Q. Ren,S. Shaull,D. Sloan,L. Song,Q. Wang,Yuhang Wang,Z. Wang,Jim White,D. Willingham,H. Wu,Ziyun Yao,M. Zhan,Genwei Zhang,Joseph A. Murray,N. Miller,Patrick Minx,Robert S. Fulton,David W. Johnson,G. Bemis,David Bentley,H. Bradshaw,S. Bourne,Matt Cordes,Zijin Du,Lucinda Fulton,D. Goela,Tina Graves,J. Hawkins,K. Hinds,K. Kemp,Phil Latreille,Dan Layman,Philip Ozersky,Tracy Rohlfing,Paul Scheet,C. Walker,A. Wamsley,Patricia Wohldmann,Kymberlie H. Pepin,Joanne O. Nelson,Ian F Korf,Joseph A. Bedell,LaDeana W. Hillier,Elaine R. Mardis,Robert H. Waterston,Richard K. Wilson,Beverly S. Emanuel,Tamim H. Shaikh,Hiroki Kurahashi,Sulagna C. Saitta,M. L. Budarf,Heather E. McDermid,Alexander Johnson,A. C.C. Wong,Bernice E. Morrow,Lisa Edelmann,U. J. Kim,Hiroaki Shizuya,Melvin I. Simon,Jan P. Dumanski,Myriam Peyrard,Darek Kedra,Eyal Seroussi,Ingegerd Fransson,I. Tapia,Carl E.G. Bruder,K. P. O'Brien +223 more
TL;DR: The sequence of the euchromatic part of human chromosome 22 is reported, which consists of 12 contiguous segments spanning 33.4 megabases, contains at least 545 genes and 134 pseudogenes, and provides the first view of the complex chromosomal landscapes that will be found in the rest of the genome.
Journal ArticleDOI
Microduplications of 16p11.2 are Associated with Schizophrenia
Shane McCarthy,Vladimir Makarov,George Kirov,Anjené M. Addington,Jon McClellan,Seungtai Yoon,Diana O. Perkins,Diane E. Dickel,Mary Kusenda,Mary Kusenda,Olga Krastoshevsky,Verena Krause,Ravinesh A. Kumar,D. Grozeva,Dheeraj Malhotra,Tom Walsh,Elaine H. Zackai,Paige Kaplan,Jaya Ganesh,Ian D. Krantz,Nancy B. Spinner,Patricia Roccanova,Abhishek Bhandari,Kevin Pavon,B. Lakshmi,B. Lakshmi,Anthony Leotta,Jude Kendall,Yoon-ha Lee,Vladimir Vacic,Sydney Gary,Lilia M. Iakoucheva,Timothy J. Crow,Susan L. Christian,Jeffrey A. Lieberman,T. Scott Stroup,Terho Lehtimäki,Kaija Puura,Chad R. Haldeman-Englert,Justin Pearl,Meredith Goodell,Virginia L. Willour,Pamela DeRosse,Jo Steele,Layla Kassem,Jessica Wolff,Nisha Chitkara,Francis J. McMahon,Anil K. Malhotra,James B. Potash,Thomas G. Schulze,Thomas G. Schulze,Markus M. Nöthen,Sven Cichon,Marcella Rietschel,Marcella Rietschel,Ellen Leibenluft,Vlad Kustanovich,Clara Lajonchere,James S. Sutcliffe,David Skuse,Michael Gill,Louise Gallagher,Nancy R. Mendell,Nicholas John Craddock,Michael John Owen,Michael Conlon O'Donovan,Tamim H. Shaikh,Ezra Susser,Lynn E. DeLisi,Lynn E. DeLisi,Patrick F. Sullivan,Curtis K. Deutsch,Curtis K. Deutsch,Judith L. Rapoport,Deborah L. Levy,Mary Claire King,Jonathan Sebat +77 more
TL;DR: A meta-analysis of datasets for multiple psychiatric disorders showed a significant association of the microduplication with schizophrenia, bipolar disorder, and autism, while the reciprocal microdeletion was associated only with autism and developmental disorders.
Journal ArticleDOI
A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay
Santhosh Girirajan,Jill A. Rosenfeld,Gregory M. Cooper,Francesca Antonacci,Priscillia Siswara,Andy Itsara,Laura Vives,Tom Walsh,Shane McCarthy,Carl Baker,Heather C Mefford,Jeffrey M. Kidd,Sharon R. Browning,Brian L. Browning,Diane E. Dickel,Deborah L. Levy,Blake C. Ballif,Kathryn Platky,Darren Farber,Gordon C. Gowans,Jessica J. Wetherbee,Alexander Asamoah,David D. Weaver,Paul R. Mark,Jennifer Dickerson,Bhuwan P. Garg,Sara Ellingwood,Rosemarie Smith,Valerie Banks,Wendy E. Smith,Marie T. McDonald,Joe J. Hoo,Beatrice N. French,Cindy Hudson,John P. Johnson,Jillian R Ozmore,John B. Moeschler,Urvashi Surti,Luis F. Escobar,Dima El-Khechen,Jerome L. Gorski,Jennifer Kussmann,Bonnie A. Salbert,Yves Lacassie,Alisha Biser,Donna M. McDonald-McGinn,Elaine H. Zackai,Matthew A. Deardorff,Tamim H. Shaikh,Eric Haan,Eric Haan,Kathryn Friend,Marco Fichera,Corrado Romano,Jozef Gecz,Jozef Gecz,Lynn E. DeLisi,Lynn E. DeLisi,Jonathan Sebat,Mary Claire King,Lisa G. Shaffer,Evan E. Eichler +61 more
TL;DR: The data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications.
Journal ArticleDOI
Chromosome 22-specific low copy repeats and the 22q11.2 deletion syndrome: genomic organization and deletion endpoint analysis
Tamim H. Shaikh,Hiroki Kurahashi,Sulagna C. Saitta,Anna Mizrahy O’Hare,Ping Hu,Bruce A. Roe,Deborah A. Driscoll,Donna M. McDonald-McGinn,Elaine H. Zackai,Marcia L. Budarf,Beverly S. Emanuel +10 more
TL;DR: The identification of chromosome 22-specific duplicated sequences or low copy repeats (LCRs) near the end-points of the 3 Mb TDR has led to the hypothesis that they mediate deletions of 22q11.2.
Journal ArticleDOI
Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes
Josephine Elia,Xiaowu Gai,Hongbo Xie,Juan C. Perin,Elizabeth A. Geiger,Joseph T. Glessner,Monica D’Arcy,R. Deberardinis,Edward C. Frackelton,Cecilia Kim,Francesca Lantieri,B. M. Muganga,Li-San Wang,Toshinobu Takeda,Eric F. Rappaport,Struan F.A. Grant,Struan F.A. Grant,Wade H. Berrettini,Marcella Devoto,Tamim H. Shaikh,Tamim H. Shaikh,Hakon Hakonarson,Hakon Hakonarson,Peter White,Peter White +24 more
TL;DR: It is suggested that rare inherited structural variations play an important role in ADHD development and a set of putative candidate genes for further study in the etiology of ADHD are indicated.