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Atsushi Hozawa
Researcher at Tohoku University
Publications - 21
Citations - 808
Atsushi Hozawa is an academic researcher from Tohoku University. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 8, co-authored 21 publications receiving 525 citations.
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Journal ArticleDOI
Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals
Masao Nagasaki,Jun Yasuda,Fumiki Katsuoka,Naoki Nariai,Kaname Kojima,Yosuke Kawai,Yumi Yamaguchi-Kabata,Junji Yokozawa,Inaho Danjoh,Sakae Saito,Yukuto Sato,Takahiro Mimori,Kaoru Tsuda,Rumiko Saito,Xiaoqing Pan,Satoshi Nishikawa,Shin Ito,Yoko Kuroki,Osamu Tanabe,Nobuo Fuse,Shinichi Kuriyama,Hideyasu Kiyomoto,Atsushi Hozawa,Naoko Minegishi,James Douglas Engel,Kengo Kinoshita,Shigeo Kure,Nobuo Yaegashi,Masayuki Yamamoto +28 more
TL;DR: The value of high-coverage sequencing for constructing population-specific variant panels, which covers 99.0% SNVs of minor allele frequency ≥0.1%, is demonstrated, and its value for identifying causal rare variants of complex human disease phenotypes in genetic association studies is demonstrated.
Journal ArticleDOI
Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective.
Shinichi Kuriyama,Hirohito Metoki,Hirohito Metoki,Masahiro Kikuya,Masahiro Kikuya,Taku Obara,Mami Ishikuro,Chizuru Yamanaka,Masato Nagai,Hiroko Matsubara,Tomoko Kobayashi,Junichi Sugawara,Gen Tamiya,Atsushi Hozawa,Naoki Nakaya,Naoki Nakaya,Naho Tsuchiya,Tomohiro Nakamura,Akira Narita,Mana Kogure,Takumi Hirata,Ichiro Tsuji,Fuji Nagami,Nobuo Fuse,Tomohiko Arai,Yoshio Kawaguchi,Shinichi Higuchi,Masaki Sakaida,Yoichi Suzuki,Noriko Osumi,Keiko Nakayama,Kiyoshi Ito,Shinichi Egawa,Koichi Chida,Eiichi Kodama,Hideyasu Kiyomoto,Tadashi Ishii,Akito Tsuboi,Hiroaki Tomita,Yasuyuki Taki,Hiroshi Kawame,Kichiya Suzuki,Naoto Ishii,Soichi Ogishima,Satoshi Mizuno,Takako Takai-Igarashi,Naoko Minegishi,Jun Yasuda,Kazuhiko Igarashi,Ritsuko Shimizu,Masao Nagasaki,Masao Nagasaki,Osamu Tanabe,Osamu Tanabe,Seizo Koshiba,Hiroaki Hashizume,Hozumi Motohashi,Teiji Tominaga,Sadayoshi Ito,Kozo Tanno,Kiyomi Sakata,Atsushi Shimizu,Jiro Hitomi,Makoto Sasaki,Kengo Kinoshita,Hiroshi Tanaka,Hiroshi Tanaka,Tadao Kobayashi,Shigeo Kure,Nobuo Yaegashi,Masayuki Yamamoto +70 more
TL;DR: This poster presents a probabilistic procedure to assess the likelihood of a person suffering from multiple organ failure and its effects on the quality of life and mortality in the event of such a situation.
Journal ArticleDOI
Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study
Atsushi Hozawa,Kozo Tanno,Naoki Nakaya,Naoki Nakaya,Tomohiro Nakamura,Naho Tsuchiya,Takumi Hirata,Akira Narita,Mana Kogure,Kotaro Nochioka,Ryohei Sasaki,Nobuyuki Takanashi,Kotaro Otsuka,Kiyomi Sakata,Shinichi Kuriyama,Masahiro Kikuya,Masahiro Kikuya,Osamu Tanabe,Osamu Tanabe,Junichi Sugawara,Kichiya Suzuki,Yoichi Suzuki,Eiichi Kodama,Nobuo Fuse,Hideyasu Kiyomoto,Hiroaki Tomita,Akira Uruno,Yohei Hamanaka,Hirohito Metoki,Hirohito Metoki,Mami Ishikuro,Taku Obara,Tomoko Kobayashi,Kazuyuki Kitatani,Kazuyuki Kitatani,Takako Takai-Igarashi,Soichi Ogishima,Mamoru Satoh,Hideki Ohmomo,Akito Tsuboi,Shinichi Egawa,Tadashi Ishii,Kiyoshi Ito,Sadayoshi Ito,Yasuyuki Taki,Naoko Minegishi,Naoto Ishii,Masao Nagasaki,Kazuhiko Igarashi,Seizo Koshiba,Ritsuko Shimizu,Gen Tamiya,Keiko Nakayama,Hozumi Motohashi,Jun Yasuda,Atsushi Shimizu,Tsuyoshi Hachiya,Yuh Shiwa,Teiji Tominaga,Hiroshi Tanaka,Hiroshi Tanaka,Kotaro Oyama,Ryoichi Tanaka,Hiroshi Kawame,Hiroshi Kawame,Akimune Fukushima,Yasushi Ishigaki,Tomoharu Tokutomi,Noriko Osumi,Tadao Kobayashi,Fuji Nagami,Hiroaki Hashizume,Tomohiko Arai,Yoshio Kawaguchi,Shinichi Higuchi,Masaki Sakaida,Ryujin Endo,Satoshi Nishizuka,Ichiro Tsuji,Jiro Hitomi,Motoyuki Nakamura,Kuniaki Ogasawara,Nobuo Yaegashi,Kengo Kinoshita,Shigeo Kure,Akio Sakai,Seiichiro Kobayashi,Kenji Sobue,Makoto Sasaki,Masayuki Yamamoto +89 more
TL;DR: This cohort comprised a large sample size and it contains information on the natural disaster, genome information, and metabolome information and enabled us to clarify the long-term effect of the disaster and also to establish personalized prevention based on genome, metabolome, and other omics information.
Journal ArticleDOI
Impact of social capital on psychological distress and interaction with house destruction and displacement after the Great East Japan Earthquake of 2011.
Naho Tsuchiya,Naoki Nakaya,Tomohiro Nakamura,Akira Narita,Mana Kogure,Jun Aida,Ichiro Tsuji,Atsushi Hozawa,Hiroaki Tomita +8 more
TL;DR: This study aimed to examine the association between social capital and psychological distress, taking into consideration the interaction of disaster‐related house condition after the Great East Japan Earthquake of 2011.
Journal ArticleDOI
Optimal number of days for home blood pressure measurement.
Teemu J. Niiranen,Teemu J. Niiranen,Kei Asayama,Kei Asayama,Lutgarde Thijs,Jouni K. Johansson,Azusa Hara,Atsushi Hozawa,Ichiro Tsuji,Takayoshi Ohkubo,Takayoshi Ohkubo,Antti Jula,Yutaka Imai,Jan A. Staessen,Jan A. Staessen +14 more
TL;DR: In this article, the authors found that even a single home BP measurement is a potent predictor of cardiovascular events, whereas seven home measurement days may be needed to reliably diagnose hypertension, regardless of the number of home measurements.