K
Kozo Tanno
Researcher at Iwate Medical University
Publications - 145
Citations - 3301
Kozo Tanno is an academic researcher from Iwate Medical University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 26, co-authored 123 publications receiving 2226 citations.
Papers
More filters
Journal ArticleDOI
Genome-wide association study identifies 112 new loci for body mass index in the Japanese population
Masato Akiyama,Yukinori Okada,Masahiro Kanai,Atsushi Takahashi,Yukihide Momozawa,Masashi Ikeda,Nakao Iwata,Shiro Ikegawa,Makoto Hirata,Koichi Matsuda,Motoki Iwasaki,Taiki Yamaji,Norie Sawada,Tsuyoshi Hachiya,Kozo Tanno,Atsushi Shimizu,Atsushi Hozawa,Naoko Minegishi,Shoichiro Tsugane,Masayuki Yamamoto,Michiaki Kubo,Yoichiro Kamatani +21 more
TL;DR: Findings provide genetic evidence that lymphocytes are relevant to body weight regulation and offer insights into the pathogenesis of obesity.
Journal ArticleDOI
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
Kazuyoshi Ishigaki,Kazuyoshi Ishigaki,Masato Akiyama,Masahiro Kanai,Masahiro Kanai,Atsushi Takahashi,Eiryo Kawakami,Hiroki Sugishita,Saori Sakaue,Saori Sakaue,Nana Matoba,Siew-Kee Low,Yukinori Okada,Chikashi Terao,Tiffany Amariuta,Tiffany Amariuta,Steven Gazal,Steven Gazal,Yuta Kochi,Momoko Horikoshi,Ken Suzuki,Ken Suzuki,Kaoru Ito,Satoshi Koyama,Kouichi Ozaki,Shumpei Niida,Yasushi Sakata,Yasuhiko Sakata,Takashi Kohno,Kouya Shiraishi,Yukihide Momozawa,Makoto Hirata,Koichi Matsuda,Masashi Ikeda,Nakao Iwata,Shiro Ikegawa,Ikuyo Kou,Toshihiro Tanaka,Hidewaki Nakagawa,Akari Suzuki,Tomomitsu Hirota,Mayumi Tamari,Kazuaki Chayama,Daiki Miki,Masaki Mori,Satoshi Nagayama,Yataro Daigo,Yataro Daigo,Yoshio Miki,Toyomasa Katagiri,Osamu Ogawa,Wataru Obara,Hidemi Ito,Teruhiko Yoshida,Issei Imoto,Takashi Takahashi,Chizu Tanikawa,Takao Suzuki,Nobuaki Sinozaki,Shiro Minami,Hiroki Yamaguchi,Satoshi Asai,Yasuo Takahashi,Ken Yamaji,Kazuhisa Takahashi,Tomoaki Fujioka,Ryo Takata,Hideki Yanai,Akihide Masumoto,Yukihiro Koretsune,Hiromu Kutsumi,Masahiko Higashiyama,Shigeo Murayama,Naoko Minegishi,Kichiya Suzuki,Kozo Tanno,Atsushi Shimizu,Taiki Yamaji,Motoki Iwasaki,Norie Sawada,Hirokazu Uemura,Hirokazu Uemura,Keitaro Tanaka,Mariko Naito,Mariko Naito,Makoto Sasaki,Kenji Wakai,Shoichiro Tsugane,Masayuki Yamamoto,Kazuhiko Yamamoto,Yoshinori Murakami,Yusuke Nakamura,Soumya Raychaudhuri,Soumya Raychaudhuri,Soumya Raychaudhuri,Johji Inazawa,Toshimasa Yamauchi,Takashi Kadowaki,Michiaki Kubo,Yoichiro Kamatani +99 more
TL;DR: A large-scale genome-wide association study in a Japanese population provides insights into the etiology of complex diseases and highlights the importance of performing GWAS in non-European populations.
Journal ArticleDOI
The Tohoku Medical Megabank Project: Design and Mission
Shinichi Kuriyama,Nobuo Yaegashi,Fuji Nagami,Tomohiko Arai,Yoshio Kawaguchi,Noriko Osumi,Masaki Sakaida,Yoichi Suzuki,Keiko Nakayama,Hiroaki Hashizume,Gen Tamiya,Hiroshi Kawame,Kichiya Suzuki,Atsushi Hozawa,Naoki Nakaya,Masahiro Kikuya,Hirohito Metoki,Ichiro Tsuji,Nobuo Fuse,Hideyasu Kiyomoto,Junichi Sugawara,Akito Tsuboi,Shinichi Egawa,Kiyoshi Ito,Koichi Chida,Tadashi Ishii,Hiroaki Tomita,Yasuyuki Taki,Naoko Minegishi,Naoto Ishii,Jun Yasuda,Kazuhiko Igarashi,Ritsuko Shimizu,Masao Nagasaki,Seizo Koshiba,Kengo Kinoshita,Soichi Ogishima,Takako Takai-Igarashi,Teiji Tominaga,Osamu Tanabe,Noriaki Ohuchi,Toru Shimosegawa,Shigeo Kure,Hiroshi Tanaka,Sadayoshi Ito,Jiro Hitomi,Kozo Tanno,Motoyuki Nakamura,Kuniaki Ogasawara,Seiichiro Kobayashi,Kiyomi Sakata,Mamoru Satoh,Atsushi Shimizu,Makoto Sasaki,Ryujin Endo,Kenji Sobue,Masayuki Yamamoto +56 more
TL;DR: An integrated biobank will be constructed based on the two prospective cohort studies, and ToMMo and IMM will investigate the chronic medical impacts of the GEJE and contribute the development of personalized healthcare and medicine worldwide.
Journal ArticleDOI
Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
Ken Suzuki,Ken Suzuki,Masato Akiyama,Kazuyoshi Ishigaki,Masahiro Kanai,Jun Hosoe,Nobuhiro Shojima,Atsushi Hozawa,Aya Kadota,Kiyonori Kuriki,Mariko Naito,Mariko Naito,Kozo Tanno,Yasushi Ishigaki,Makoto Hirata,Koichi Matsuda,Nakao Iwata,Masashi Ikeda,Norie Sawada,Taiki Yamaji,Motoki Iwasaki,Shiro Ikegawa,Shiro Maeda,Yoshinori Murakami,Kenji Wakai,Shoichiro Tsugane,Makoto Sasaki,Masayuki Yamamoto,Yukinori Okada,Michiaki Kubo,Yoichiro Kamatani,Momoko Horikoshi,Toshimasa Yamauchi,Takashi Kadowaki,Takashi Kadowaki +34 more
TL;DR: Genome-wide association analyses identify 28 new susceptibility loci for type 2 diabetes in the Japanese population, including missense variants in genes related to pancreatic acinar cells (GP2) and insulin secretion (GLP1R).
Journal ArticleDOI
Characterizing rare and low-frequency height-associated variants in the Japanese population.
Masato Akiyama,Kazuyoshi Ishigaki,Saori Sakaue,Yukihide Momozawa,Momoko Horikoshi,Makoto Hirata,Koichi Matsuda,Shiro Ikegawa,Atsushi Takahashi,Masahiro Kanai,Sadao Suzuki,Daisuke Matsui,Mariko Naito,Taiki Yamaji,Motoki Iwasaki,Norie Sawada,Kozo Tanno,Makoto Sasaki,Atsushi Hozawa,Naoko Minegishi,Kenji Wakai,Shoichiro Tsugane,Atsushi Shimizu,Masayuki Yamamoto,Yukinori Okada,Yoshinori Murakami,Michiaki Kubo,Yoichiro Kamatani +27 more
TL;DR: A genotype reference panel for the Japanese population followed by GWAS is constructed and a gene-based analysis identifies two genes with multiple height-increasing rare and low-frequency nonsynonymous variants, suggesting that height-associated rare variants are under different selection pressure in Japanese and European populations.