Y
Yoichi Suzuki
Researcher at Chiba University
Publications - 186
Citations - 7459
Yoichi Suzuki is an academic researcher from Chiba University. The author has contributed to research in topics: Single-nucleotide polymorphism & Holocarboxylase synthetase. The author has an hindex of 45, co-authored 174 publications receiving 6604 citations. Previous affiliations of Yoichi Suzuki include Indiana University & Tohoku University.
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Journal ArticleDOI
Germline mutations in HRAS proto-oncogene cause Costello syndrome
Yoko Aoki,Tetsuya Niihori,Hiroshi Kawame,Kenji Kurosawa,Hirofumi Ohashi,Yukichi Tanaka,Mirella Filocamo,Kumi Kato,Yoichi Suzuki,Shigeo Kure,Yoichi Matsubara +10 more
TL;DR: Four heterozygous de novo mutations of HRAS are identified in 12 of 13 affected individuals, suggesting that germline mutations in HRAS perturb human development and increase susceptibility to tumors.
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A genome-wide association study identifies RNF213 as the first Moyamoya disease gene
Fumiaki Kamada,Yoko Aoki,Ayumi Narisawa,Yu Abe,Shoko Komatsuzaki,Atsuo Kikuchi,Junko Kanno,Tetsuya Niihori,Masao Ono,Naoto Ishii,Yuji Owada,Miki Fujimura,Yoichi Mashimo,Yoichi Suzuki,Akira Hata,Shigeru Tsuchiya,Teiji Tominaga,Yoichi Matsubara,Shigeo Kure +18 more
TL;DR: Results indicate that RNF213 is the first identified susceptibility gene for MMD, and it is confirmed that mature lymphocytes express higher levels of Rnf213 mRNA than their immature counterparts.
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A genome-wide association study identifies three new risk loci for Kawasaki disease
Yoshihiro Onouchi,Kouichi Ozaki,Jane C. Burns,Jane C. Burns,Chisato Shimizu,Chisato Shimizu,Masaru Terai,Hiromichi Hamada,Takafumi Honda,Hiroyuki Suzuki,Tomohiro Suenaga,Takashi Takeuchi,Norishige Yoshikawa,Yoichi Suzuki,Kumi Yasukawa,Ryota Ebata,Kouji Higashi,Tsutomu Saji,Yasushi Kemmotsu,Shinichi Takatsuki,Kazunobu Ouchi,Fumio Kishi,Tetsushi Yoshikawa,Toshiro Nagai,Kunihiro Hamamoto,Yoshitake Sato,Akihito Honda,Hironobu Kobayashi,Junichi Sato,Shoichi Shibuta,Masakazu Miyawaki,Ko Oishi,Hironobu Yamaga,Noriyuki Aoyagi,Seiji Iwahashi,Ritsuko Miyashita,Yuji Murata,Kumiko Sasago,Atsushi Takahashi,Naoyuki Kamatani,Michiaki Kubo,Tatsuhiko Tsunoda,Akira Hata,Yusuke Nakamura,Toshihiro Tanaka +44 more
TL;DR: A genome-wide association study of Kawasaki disease in Japanese subjects using data from 428 individuals with Kawasaki Disease and 3,379 controls genotyped at 473,803 SNPs provides new insights into the pathogenesis and pathophysiology of Kaw Osaka disease.
Journal ArticleDOI
Type 1 Phosphatase, a Negative Regulator of Cardiac Function
Andrew N. Carr,Albrecht Schmidt,Yoichi Suzuki,Federica del Monte,Yoji Sato,Carita Lanner,Kristine Breeden,Shao Ling Jing,Patrick B. Allen,Paul Greengard,Atsuko Yatani,Brian D. Hoit,Ingrid L. Grupp,Roger J. Hajjar,Anna A. DePaoli-Roach,Evangelia G. Kranias +15 more
TL;DR: PP1 is an important regulator of cardiac function, and inhibition of its activity may represent a novel therapeutic target in heart failure.
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The Tohoku Medical Megabank Project: Design and Mission
Shinichi Kuriyama,Nobuo Yaegashi,Fuji Nagami,Tomohiko Arai,Yoshio Kawaguchi,Noriko Osumi,Masaki Sakaida,Yoichi Suzuki,Keiko Nakayama,Hiroaki Hashizume,Gen Tamiya,Hiroshi Kawame,Kichiya Suzuki,Atsushi Hozawa,Naoki Nakaya,Masahiro Kikuya,Hirohito Metoki,Ichiro Tsuji,Nobuo Fuse,Hideyasu Kiyomoto,Junichi Sugawara,Akito Tsuboi,Shinichi Egawa,Kiyoshi Ito,Koichi Chida,Tadashi Ishii,Hiroaki Tomita,Yasuyuki Taki,Naoko Minegishi,Naoto Ishii,Jun Yasuda,Kazuhiko Igarashi,Ritsuko Shimizu,Masao Nagasaki,Seizo Koshiba,Kengo Kinoshita,Soichi Ogishima,Takako Takai-Igarashi,Teiji Tominaga,Osamu Tanabe,Noriaki Ohuchi,Toru Shimosegawa,Shigeo Kure,Hiroshi Tanaka,Sadayoshi Ito,Jiro Hitomi,Kozo Tanno,Motoyuki Nakamura,Kuniaki Ogasawara,Seiichiro Kobayashi,Kiyomi Sakata,Mamoru Satoh,Atsushi Shimizu,Makoto Sasaki,Ryujin Endo,Kenji Sobue,Masayuki Yamamoto +56 more
TL;DR: An integrated biobank will be constructed based on the two prospective cohort studies, and ToMMo and IMM will investigate the chronic medical impacts of the GEJE and contribute the development of personalized healthcare and medicine worldwide.