T
Tadashi Ishii
Researcher at Tohoku University
Publications - 143
Citations - 1352
Tadashi Ishii is an academic researcher from Tohoku University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 110 publications receiving 691 citations. Previous affiliations of Tadashi Ishii include Tohoku Pharmaceutical University.
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Journal ArticleDOI
The Tohoku Medical Megabank Project: Design and Mission
Shinichi Kuriyama,Nobuo Yaegashi,Fuji Nagami,Tomohiko Arai,Yoshio Kawaguchi,Noriko Osumi,Masaki Sakaida,Yoichi Suzuki,Keiko Nakayama,Hiroaki Hashizume,Gen Tamiya,Hiroshi Kawame,Kichiya Suzuki,Atsushi Hozawa,Naoki Nakaya,Masahiro Kikuya,Hirohito Metoki,Ichiro Tsuji,Nobuo Fuse,Hideyasu Kiyomoto,Junichi Sugawara,Akito Tsuboi,Shinichi Egawa,Kiyoshi Ito,Koichi Chida,Tadashi Ishii,Hiroaki Tomita,Yasuyuki Taki,Naoko Minegishi,Naoto Ishii,Jun Yasuda,Kazuhiko Igarashi,Ritsuko Shimizu,Masao Nagasaki,Seizo Koshiba,Kengo Kinoshita,Soichi Ogishima,Takako Takai-Igarashi,Teiji Tominaga,Osamu Tanabe,Noriaki Ohuchi,Toru Shimosegawa,Shigeo Kure,Hiroshi Tanaka,Sadayoshi Ito,Jiro Hitomi,Kozo Tanno,Motoyuki Nakamura,Kuniaki Ogasawara,Seiichiro Kobayashi,Kiyomi Sakata,Mamoru Satoh,Atsushi Shimizu,Makoto Sasaki,Ryujin Endo,Kenji Sobue,Masayuki Yamamoto +56 more
TL;DR: An integrated biobank will be constructed based on the two prospective cohort studies, and ToMMo and IMM will investigate the chronic medical impacts of the GEJE and contribute the development of personalized healthcare and medicine worldwide.
Journal ArticleDOI
Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective.
Shinichi Kuriyama,Hirohito Metoki,Hirohito Metoki,Masahiro Kikuya,Masahiro Kikuya,Taku Obara,Mami Ishikuro,Chizuru Yamanaka,Masato Nagai,Hiroko Matsubara,Tomoko Kobayashi,Junichi Sugawara,Gen Tamiya,Atsushi Hozawa,Naoki Nakaya,Naoki Nakaya,Naho Tsuchiya,Tomohiro Nakamura,Akira Narita,Mana Kogure,Takumi Hirata,Ichiro Tsuji,Fuji Nagami,Nobuo Fuse,Tomohiko Arai,Yoshio Kawaguchi,Shinichi Higuchi,Masaki Sakaida,Yoichi Suzuki,Noriko Osumi,Keiko Nakayama,Kiyoshi Ito,Shinichi Egawa,Koichi Chida,Eiichi Kodama,Hideyasu Kiyomoto,Tadashi Ishii,Akito Tsuboi,Hiroaki Tomita,Yasuyuki Taki,Hiroshi Kawame,Kichiya Suzuki,Naoto Ishii,Soichi Ogishima,Satoshi Mizuno,Takako Takai-Igarashi,Naoko Minegishi,Jun Yasuda,Kazuhiko Igarashi,Ritsuko Shimizu,Masao Nagasaki,Masao Nagasaki,Osamu Tanabe,Osamu Tanabe,Seizo Koshiba,Hiroaki Hashizume,Hozumi Motohashi,Teiji Tominaga,Sadayoshi Ito,Kozo Tanno,Kiyomi Sakata,Atsushi Shimizu,Jiro Hitomi,Makoto Sasaki,Kengo Kinoshita,Hiroshi Tanaka,Hiroshi Tanaka,Tadao Kobayashi,Shigeo Kure,Nobuo Yaegashi,Masayuki Yamamoto +70 more
TL;DR: This poster presents a probabilistic procedure to assess the likelihood of a person suffering from multiple organ failure and its effects on the quality of life and mortality in the event of such a situation.
Journal ArticleDOI
Chronic Running Exercise Alleviates Early Progression of Nephropathy with Upregulation of Nitric Oxide Synthases and Suppression of Glycation in Zucker Diabetic Rats
Daisuke Ito,Pengyu Cao,Takaaki Kakihana,Emiko Sato,Chihiro Suda,Yoshikazu Muroya,Yoshiko Ogawa,Gaizun Hu,Tadashi Ishii,Osamu Ito,Masahiro Kohzuki,Hideyasu Kiyomoto +11 more
TL;DR: It is suggested that upregulation of NOS expression, suppression of NADPH oxidase and α-oxoaldehydes in the kidneys may contribute to the renal protective effects of exercise in the early progression of diabetic nephropathy in ZDF rats.
Journal ArticleDOI
Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study
Atsushi Hozawa,Kozo Tanno,Naoki Nakaya,Naoki Nakaya,Tomohiro Nakamura,Naho Tsuchiya,Takumi Hirata,Akira Narita,Mana Kogure,Kotaro Nochioka,Ryohei Sasaki,Nobuyuki Takanashi,Kotaro Otsuka,Kiyomi Sakata,Shinichi Kuriyama,Masahiro Kikuya,Masahiro Kikuya,Osamu Tanabe,Osamu Tanabe,Junichi Sugawara,Kichiya Suzuki,Yoichi Suzuki,Eiichi Kodama,Nobuo Fuse,Hideyasu Kiyomoto,Hiroaki Tomita,Akira Uruno,Yohei Hamanaka,Hirohito Metoki,Hirohito Metoki,Mami Ishikuro,Taku Obara,Tomoko Kobayashi,Kazuyuki Kitatani,Kazuyuki Kitatani,Takako Takai-Igarashi,Soichi Ogishima,Mamoru Satoh,Hideki Ohmomo,Akito Tsuboi,Shinichi Egawa,Tadashi Ishii,Kiyoshi Ito,Sadayoshi Ito,Yasuyuki Taki,Naoko Minegishi,Naoto Ishii,Masao Nagasaki,Kazuhiko Igarashi,Seizo Koshiba,Ritsuko Shimizu,Gen Tamiya,Keiko Nakayama,Hozumi Motohashi,Jun Yasuda,Atsushi Shimizu,Tsuyoshi Hachiya,Yuh Shiwa,Teiji Tominaga,Hiroshi Tanaka,Hiroshi Tanaka,Kotaro Oyama,Ryoichi Tanaka,Hiroshi Kawame,Hiroshi Kawame,Akimune Fukushima,Yasushi Ishigaki,Tomoharu Tokutomi,Noriko Osumi,Tadao Kobayashi,Fuji Nagami,Hiroaki Hashizume,Tomohiko Arai,Yoshio Kawaguchi,Shinichi Higuchi,Masaki Sakaida,Ryujin Endo,Satoshi Nishizuka,Ichiro Tsuji,Jiro Hitomi,Motoyuki Nakamura,Kuniaki Ogasawara,Nobuo Yaegashi,Kengo Kinoshita,Shigeo Kure,Akio Sakai,Seiichiro Kobayashi,Kenji Sobue,Makoto Sasaki,Masayuki Yamamoto +89 more
TL;DR: This cohort comprised a large sample size and it contains information on the natural disaster, genome information, and metabolome information and enabled us to clarify the long-term effect of the disaster and also to establish personalized prevention based on genome, metabolome, and other omics information.
Journal ArticleDOI
Difference in the Source of Anti-AQP4-IgG and Anti-MOG-IgG Antibodies in CSF in Patients With Neuromyelitis Optica Spectrum Disorder
Tetsuya Akaishi,Toshiyuki Takahashi,Tatsuro Misu,Kimihiko Kaneko,Yoshiki Takai,Shuhei Nishiyama,Ryo Ogawa,Juichi Fujimori,Tadashi Ishii,Masashi Aoki,Kazuo Fujihara,Ichiro Nakashima +11 more
TL;DR: In this paper, the differences in the source and the level of intrathecal synthesis between anti-aquaporin-4 antibodies (AQP4-IgG) and anti-myelin oligodendrocyte glycoprotein antibodies (MOG-G) were studied for the antibody titers in the sera and CSF simultaneously collected in the acute attacks.