Aurore Curie

TL;DR: An antagonist for the metabotropic glutamate receptor may improve symptoms in patients with fragile X syndrome whose FMR1 promoters are fully methylated, a sign that gene expression is completely silenced, and provides the basis for a larger study to test whether methylation can serve as a predictor of a positive antagonist response in a population of patients with Fragile X syndrome.

TL;DR: FXS is at the forefront of efforts to develop drugs for neurodevelopmental disorders, and lessons learned in the process will also be important for such disorders.

TL;DR: Acting in a social context induced analogous modulations of motor and sensorimotor regions in observer and actor and sharing a common goal during an interaction seems thus to evoke a common representation of the global action that includes both actor and observer movements.

TL;DR: The Renpenning syndrome spectrum: new clinical insights supported by 13 new PQBP1‐mutated males is presented.

TL;DR: The phenotypic spectrum of Allan–Herndon–Dudley syndrome is extended to a mild intellectual disability with hypotonia, which may be adversely affected by neuro‐orthopaedic, pulmonary, and epileptic complications.