Aymeric Neyret

TL;DR: It is shown that human dermal fibroblasts, epidermal keratinocytes, and immature dendritic cells are permissive to the most recent ZikV isolate, responsible for the epidemic in French Polynesia, and a major role is shown for the phosphatidylserine receptor AXL as a ZIKV entry receptor and for cellular autophagy in enhancing ZIKv replication in permissive cells.

TL;DR: Coxiella vacuolar protein B (CvpB) is described as a Coxiella effector that interacts with phosphoinositides on host cell membranes and manipulates phosphatidylinositol 3-phosphate [PI(3)P] metabolism for optimalcoxiella-containing vacuole (CCV) development.

TL;DR: A CFTR-depleted zebrafish model is exploited, recapitulating CF immuno-pathogenesis, to study the contribution of CFTR in innate immunity against M. abscessus by mounting effective oxidative responses.

TL;DR: It is reported that chikungunya virus rapidly elicits an innate immune response in these cells leading to the enhanced transcription of type I/II and type III interferon genes, and keratinocytes behave as an antiviral defense against CHIKV infection rather than as a primary targets for initial replication.

TL;DR: The results highlight the role of GagNC in the spatiotemporal control of RTion, via an ESCRT-I-dependent mechanism and reveal that DNA virus production is the consequence of budding defects associated with Gag aggregation at the plasma membrane and deficiency in the recruitment of Tsg101, a key ESC RT-I component.