B
B.K. Park
Researcher at University of Liverpool
Publications - 194
Citations - 9088
B.K. Park is an academic researcher from University of Liverpool. The author has contributed to research in topics: Metabolite & Microsome. The author has an hindex of 55, co-authored 192 publications receiving 8716 citations. Previous affiliations of B.K. Park include University of Bern & Western Infirmary.
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Drug-protein conjugates. X: The role of protein conjugation in the disposition of dinitrofluorobenzene
TL;DR: The metabolism and irreversible protein binding of 2,4-[3,5-3H]dinitrofluorobenzene (3H-DNFB), a model chemically reactive compound, were studied in the rat and the metabolites were extensively eliminated in bile and urine.
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Inhibition of dapsone-induced methaemoglobinaemia in the rat.
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Phenobarbitone effects on hepatic microsomal enzymes and liver blood flow in the guinea pig.
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Cortisol metabolism by human liver in vitro—IV. Metabolism of 9α-fluorocortisol by human liver microsomes and cytosol
TL;DR: The oxidative and reductive biotransformations of 9alpha-fluorocortisol by human liver microsomes and cytosol have been characterized and their mechanistic basis is discussed with reference to the electronic and conformational changes induced by 9 alpha- fluorination.
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HLA‐DQ allele‐restricted activation of nitroso sulfamethoxazole‐specific CD4‐positive T lymphocytes from patients with cystic fibrosis
Monday O. Ogese,Katy Saide,Lee Faulkner,Paul Whitaker,Daniel Peckham,Ana Alfirevic,D. M. Baker,Alessandro Sette,Munir Pirmohamed,B.K. Park,Dean J. Naisbitt +10 more
TL;DR: It is assumed that the derived peptide antigens interact with a number of HLA molecules to activate T cells; however, HLA restriction of the drug metabolite‐specific T‐cell response has not been studied.