Barbara Walzog

TL;DR: The results identify a previously unknown role for NG2+ pericytes as an active component of innate immune responses, which supports the immunosurveillance and effector function of extravasated neutrophils and macrophages.

TL;DR: Cyclines can affect the ratio of Bax-/Bcl-Xl expression in human PMN and modulate the subsequent activity of caspase-3, which functions as executer of the programmed cell death and may promote apoptosis by a positive feed-forward mechanism that downregulates Bcl- Xl.

TL;DR: The results point to a signaling cascade from L-selectin via p56lck, Grb2/Sos, Ras, and Rac2 to 2-O.

TL;DR: The data demonstrates that the paracrine secretion of growth factors is essential for cellular differentiation in wound healing, and in neutrophil–macrophage cocultures, lack of CD18 on either cell type leads to dramatically reduced TGF‐β1 release by macrophages due to defective adhesion to, and subsequent impaired phagocytic clearance of, neutrophils.

TL;DR: It is shown that trauma-induced leukocyte adhesion in cremaster muscle venules is strongly dependent on RAGE and ICAM-1 acting together in an overlapping fashion, and a crucial role of endothelium-expressed RAGE as Mac-1 ligand is indicated.