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Béatrice Cambien
Researcher at University of Nice Sophia Antipolis
Publications - 30
Citations - 1822
Béatrice Cambien is an academic researcher from University of Nice Sophia Antipolis. The author has contributed to research in topics: Genetic enhancement & Cancer. The author has an hindex of 15, co-authored 30 publications receiving 1690 citations. Previous affiliations of Béatrice Cambien include French Institute of Health and Medical Research & Commissariat à l'énergie atomique et aux énergies alternatives.
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Journal ArticleDOI
Nitric Oxide Regulates Exocytosis by S-Nitrosylation of N-ethylmaleimide-Sensitive Factor
Kenji Matsushita,Craig N. Morrell,Béatrice Cambien,Shui Xiang Yang,Munekazu Yamakuchi,Clare Bao,Makoto R. Hara,Richard A. Quick,Wangsen Cao,Brian O'Rourke,John M. Lowenstein,Jonathan Pevsner,Denisa D. Wagner,Charles J. Lowenstein +13 more
TL;DR: It is shown that NO inhibits exocytosis of Weibel-Palade bodies, endothelial granules that mediate vascular inflammation and thrombosis, by regulating the activity of N-ethylmaleimide-sensitive factor (NSF).
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Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.
Ingrid Hrachovinova,Béatrice Cambien,Ali Hafezi-Moghadam,János Kappelmayer,Raymond T Camphausen,Angela Widom,Lijun Xia,Haig H. Kazazian,Robert G. Schaub,Rodger P. McEver,Denisa D. Wagner +10 more
TL;DR: P-sel–Ig treatment could become a new approach to sustained control of bleeding in hemophilia by inducing formation of procoagulant microparticles in human blood through P-selectin glycoprotein ligand-1 (PSGL-1; encoded by the Psgl1 gene, officially known as Selpl).
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Signal transduction involved in MCP-1–mediated monocytic transendothelial migration
TL;DR: Coordinated action of distinct signal pathways is required to produce a full response to MCP-1 in terms of monocytic locomotion, and the results underscore the major implication of Go/Gi proteins and nonreceptor tyrosine kinases in the early MCP
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Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism
Béatrice Cambien,Babou Fahardine Karimdjee,Babou Fahardine Karimdjee,Peggy Richard-Fiardo,Peggy Richard-Fiardo,H. Bziouech,H. Bziouech,Robert Barthel,Robert Barthel,Marc-Alban Millet,Marc-Alban Millet,V. Martini,V. Martini,Daniel Birnbaum,J. Y. Scoazec,J. Abello,T al Saati,Michael G. Johnson,Timothy J. Sullivan,Julio C. Medina,Tassie L. Collins,Annie Schmid-Alliana,Annie Schmid-Alliana,Heidy Schmid-Antomarchi,Heidy Schmid-Antomarchi +24 more
TL;DR: It is indicated that activation of CXCR3 receptors by its cognate ligands facilitates the implantation and the progression of CRC cells within lung tissues and that inhibition of this axis decreases pulmonary metastasis of CRC in two murine tumour models.
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A new role in hemostasis for the adhesion receptor P-selectin.
TL;DR: The adhesion receptor P-selectin has long been known to support leukocyte rolling and emigration at sites of inflammation, and recent developments suggest that the procoagulant potential of P- selectin could be used to treat coagulation disorders such as hemophilia A.