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Benedikt Schaefer
Researcher at Innsbruck Medical University
Publications - 59
Citations - 959
Benedikt Schaefer is an academic researcher from Innsbruck Medical University. The author has contributed to research in topics: Medicine & Liver transplantation. The author has an hindex of 13, co-authored 46 publications receiving 475 citations. Previous affiliations of Benedikt Schaefer include Environment Agency.
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Journal ArticleDOI
Iron-induced hypophosphatemia: an emerging complication.
TL;DR: Treatment is guided by the severity of hypophosphatemia, and most patients will require oral or intravenous phosphate substitution, and future treatment options could involve therapeutic anti-FGF23 antibody (KRN23).
Journal ArticleDOI
A time-resolved proteomic and prognostic map of COVID-19.
Vadim Demichev,Vadim Demichev,Vadim Demichev,Pinkus Tober-Lau,Oliver Lemke,Tatiana Nazarenko,Charlotte Thibeault,Harry J. Whitwell,Annika Röhl,Anja Freiwald,Lukasz Szyrwiel,Daniela Ludwig,Clara Correia-Melo,Simran Kaur Aulakh,Elisa T Helbig,Paula Stubbemann,Lena J Lippert,Nana-Maria Grüning,Oleg Blyuss,Spyros I. Vernardis,Matthew White,Christoph B. Messner,Michael Joannidis,Thomas Sonnweber,Sebastian J. Klein,Alex Pizzini,Yvonne Wohlfarter,Sabina Sahanic,Richard Hilbe,Benedikt Schaefer,Sonja Wagner,Mirja Mittermaier,Felix Machleidt,Carmen Garcia,Christoph Ruwwe-Glösenkamp,Tilman Lingscheid,Laure Bosquillon de Jarcy,Miriam Stegemann,Moritz Pfeiffer,Linda Jürgens,Sophy Denker,Daniel Zickler,Philipp Enghard,Aleksej Zelezniak,Archie Campbell,Caroline Hayward,David J. Porteous,Riccardo E. Marioni,Alexander Uhrig,Holger Müller-Redetzky,Heinz Zoller,Judith Löffler-Ragg +51 more
TL;DR: In this paper, the authors characterized the time-dependent progression of the disease in 139 COVID-19 inpatients by measuring 86 accredited diagnostic parameters, such as blood cell counts and enzyme activities, as well as untargeted plasma proteomes at 687 sampling points.
Journal ArticleDOI
Choice of High-Dose Intravenous Iron Preparation Determines Hypophosphatemia Risk.
Benedikt Schaefer,Philipp Würtinger,Armin Finkenstedt,Vickie Braithwaite,André Viveiros,Maria Effenberger,Irene Sulzbacher,Alexander R. Moschen,Andrea Griesmacher,Herbert Tilg,Wolfgang Vogel,Heinz Zoller +11 more
TL;DR: A significant increase in the phosphaturic hormone intact FGF-23 in hypophosphatemic patients shows that this adverse event is caused by FCM-induced hormone dysregulation.
Journal ArticleDOI
Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation
Karim Hamesch,Mattias Mandorfer,V Pereira,LS Moeller,Mònica Pons,Mònica Pons,Grace E. Dolman,Matthias C. Reichert,Carolin V. Schneider,V Woditsch,J. Voss,C Lindhauer,Malin Fromme,I. Spivak,Nurdan Guldiken,Biaohuan Zhou,A Arslanow,A Arslanow,Benedikt Schaefer,Heinz Zoller,Elmar Aigner,Thomas Reiberger,M Wetzel,Britta Siegmund,Carolina Simões,Rui Gaspar,Luís Maia,Dalila Costa,Mario Bento-Miranda,Josef van Helden,Eray Yagmur,Danilo Bzdok,Jan Stolk,Wolfgang Gleiber,Verena Knipel,Wolfram Windisch,Ravi Mahadeva,Robert Bals,Rembert Koczulla,Miriam Barrecheguren,Marc Miravitlles,Sabina Janciauskiene,Felix Stickel,Frank Lammert,Rodrigo Liberal,Joan Genescà,Joan Genescà,William J.H. Griffiths,Michael Trauner,Aleksander Krag,Christian Trautwein,Pavel Strnad +51 more
TL;DR: Evidence of liver steatosis and impaired lipid secretion is found in studies of AATD patients with the Pi*ZZ mutation, and of Pi*Z-overexpressing mice, and factors associated with significant liver fibrosis in patients are identified.
Journal ArticleDOI
Heterozygosity for the alpha-1-antitrypsin Z allele in cirrhosis is associated with more advanced disease.
Benedikt Schaefer,Mattias Mandorfer,André Viveiros,Armin Finkenstedt,Peter Ferenci,Stefan Schneeberger,Herbert Tilg,Heinz Zoller +7 more
TL;DR: The genotype MZ is a genetic risk factor for more advanced cirrhosis and decompensation and MZ patients with cir rhosis and hypotransferrinemia or increased Tf saturation are at higher risk of death and liver transplantation.