S
Sebastian J. Klein
Researcher at Innsbruck Medical University
Publications - 42
Citations - 767
Sebastian J. Klein is an academic researcher from Innsbruck Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 31 publications receiving 350 citations.
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Journal ArticleDOI
Lung–kidney interactions in critically ill patients: consensus report of the Acute Disease Quality Initiative (ADQI) 21 Workgroup
Michael Joannidis,Lui G. Forni,Lui G. Forni,Sebastian J. Klein,Patrick M. Honore,Kianoush Kashani,Marlies Ostermann,John R. Prowle,John R. Prowle,Sean M. Bagshaw,Vincenzo Cantaluppi,Michael Darmon,Michael Darmon,Michael Darmon,Xiaoqiang Ding,Valentin Fuhrmann,Eric Hoste,Faeq Husain-Syed,Matthias Lubnow,Marco Maggiorini,Melanie Meersch,Patrick T. Murray,Zaccaria Ricci,Kai Singbartl,Thomas Staudinger,Tobias Welte,Claudio Ronco,John A. Kellum +27 more
TL;DR: Lung protective ventilation, conservative fluid management and early recognition and treatment of pulmonary infections were the only clinical recommendations with higher quality of evidence found in the ADQI 21 conference.
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Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis.
Sebastian J. Klein,Anna K. Brandtner,Georg F. Lehner,Hanno Ulmer,Sean M. Bagshaw,Christian J. Wiedermann,Michael Joannidis +6 more
TL;DR: Though several biomarkers showed promise and reasonable prediction of RRT use for critically ill patients with AKI, the strength of evidence currently precludes their routine use to guide decision-making on when to initiate RRT.
Journal ArticleDOI
A time-resolved proteomic and prognostic map of COVID-19.
Vadim Demichev,Vadim Demichev,Vadim Demichev,Pinkus Tober-Lau,Oliver Lemke,Tatiana Nazarenko,Charlotte Thibeault,Harry J. Whitwell,Annika Röhl,Anja Freiwald,Lukasz Szyrwiel,Daniela Ludwig,Clara Correia-Melo,Simran Kaur Aulakh,Elisa T Helbig,Paula Stubbemann,Lena J Lippert,Nana-Maria Grüning,Oleg Blyuss,Spyros I. Vernardis,Matthew White,Christoph B. Messner,Michael Joannidis,Thomas Sonnweber,Sebastian J. Klein,Alex Pizzini,Yvonne Wohlfarter,Sabina Sahanic,Richard Hilbe,Benedikt Schaefer,Sonja Wagner,Mirja Mittermaier,Felix Machleidt,Carmen Garcia,Christoph Ruwwe-Glösenkamp,Tilman Lingscheid,Laure Bosquillon de Jarcy,Miriam Stegemann,Moritz Pfeiffer,Linda Jürgens,Sophy Denker,Daniel Zickler,Philipp Enghard,Aleksej Zelezniak,Archie Campbell,Caroline Hayward,David J. Porteous,Riccardo E. Marioni,Alexander Uhrig,Holger Müller-Redetzky,Heinz Zoller,Judith Löffler-Ragg +51 more
TL;DR: In this paper, the authors characterized the time-dependent progression of the disease in 139 COVID-19 inpatients by measuring 86 accredited diagnostic parameters, such as blood cell counts and enzyme activities, as well as untargeted plasma proteomes at 687 sampling points.
Journal ArticleDOI
Impaired fibrinolysis in critically ill COVID-19 patients.
Mirjam Bachler,Johannes Bösch,Daniel P. Stürzel,Tobias Hell,Andreas Giebl,Mathias Ströhle,Sebastian J. Klein,Volker Schäfer,Georg F. Lehner,Michael Joannidis,Claudius Thomé,Dietmar Fries +11 more
TL;DR: Critically ill COVID-19 patients have impaired fibrinolytic response and showed hypercoagulability in ClotPro assays, a viscoelastic whole blood coagulation testing device.
Journal ArticleDOI
Oliguria in critically ill patients: a narrative review
TL;DR: This work aims to explore the clinical relevance of oliguria in critically ill patients and propose a clinical pathway for the diagnostic and therapeutic management of an oliguric, critically ill patient.