Pavel Strnad

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The importance of the liver as a guardian, modifier and target of sepsis, the factors that contribute to seps isis in patients with liver cirrhosis and new therapeutic strategies are reviewed.

TL;DR: Data that corroborate the view that IFs function as highly specialized cytoskeletal stress proteins that promote cellular organization and homeostasis are reviewed.

TL;DR: Acute decompensation without ACLF is a heterogeneous condition with three different clinical courses and two major pathophysiological mechanisms: systemic inflammation and portal hypertension.

TL;DR: The understanding of keratins is shifting from diagnostic markers to active disease modifiers, suggesting that these changes modulate multiple processes including cell migration, tumor growth/metastasis and development of infections.