B
Benjamin Mary
Researcher at University of Strasbourg
Publications - 7
Citations - 209
Benjamin Mary is an academic researcher from University of Strasbourg. The author has contributed to research in topics: RALB & RALA. The author has an hindex of 3, co-authored 6 publications receiving 105 citations. Previous affiliations of Benjamin Mary include French Institute of Health and Medical Research.
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Journal ArticleDOI
Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo
Vincent Hyenne,Shima Ghoroghi,Shima Ghoroghi,Mayeul Collot,Joanna Bons,Gautier Follain,Gautier Follain,Sébastien Harlepp,Sébastien Harlepp,Benjamin Mary,Benjamin Mary,Jack Bauer,Jack Bauer,Luc Mercier,Luc Mercier,Ignacio Busnelli,Ignacio Busnelli,Olivier Lefebvre,Olivier Lefebvre,Nina Fekonja,Nina Fekonja,Maria Jesus Garcia-Leon,Maria Jesus Garcia-Leon,Pedro Machado,François Delalande,Ana Amor López,Susana Garcia Silva,Frederik J. Verweij,Frederik J. Verweij,Guillaume van Niel,Guillaume van Niel,Farida Djouad,Héctor Peinado,Christine Carapito,Andrey S. Klymchenko,Jacky G. Goetz,Jacky G. Goetz +36 more
TL;DR: This study proves the usefulness and prospects of zebrafish embryo to track tumor EVs and dissect their role in metastatic niches formation in vivo and demonstrates that tumor EVs activate macrophages and promote metastatic outgrowth.
Journal ArticleDOI
Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes.
Shima Ghoroghi,Shima Ghoroghi,Benjamin Mary,Benjamin Mary,Annabel Larnicol,Annabel Larnicol,Nandini Asokan,Nandini Asokan,Annick Klein,Annick Klein,Naël Osmani,Naël Osmani,Ignacio Busnelli,Ignacio Busnelli,François Delalande,Nicodème Paul,Nicodème Paul,Sébastien Halary,Frédéric Gros,Frédéric Gros,Laetitia Fouillen,Anne-Marie Haeberlé,Catherine A. Royer,Coralie Spiegelhalter,Gwennan André-Grégoire,Vincent Mittelheisser,Alexandre Detappe,Kendelle J. Murphy,Kendelle J. Murphy,Paul Timpson,Paul Timpson,Raphael Carapito,Raphael Carapito,Marcel Blot-Chabaud,Julie Gavard,Christine Carapito,Nicolas Vitale,Olivier Lefebvre,Olivier Lefebvre,Jacky G. Goetz,Jacky G. Goetz,Vincent Hyenne +41 more
TL;DR: In this paper, the authors show that GTPases of the Ral family control multi-vesicular bodies homeostasis and tune the biogenesis and secretion of pro-metastatic EVs.
Journal ArticleDOI
Tumor extracellular vesicles drive metastasis (it's a long way from home).
TL;DR: The journey of extracellular vesicles from the primary tumor to the future metastatic organ, with a focus on the mechanisms used by EVs to target organs with a specific tropism (i.e., organotropism), and the formation of a pro‐inflammatory and immuno‐tolerant microenvironment is described.
Book ChapterDOI
Live tracking of extracellular vesicles in larval zebrafish.
TL;DR: The experimental procedures that are built for dissecting the dissemination of EVs at high spatio-temporal resolution in vivo are described, finding that some conceptual gaps are direct consequences of the difficulty to visualize the shuttling and targeting of EVs in real time in vivo.
Posted ContentDOI
Ral GTPases promote metastasis by controlling biogenesis and organ colonization of exosomes
Shima Ghoroghi,Benjamin Mary,Annabel Larnicol,Annick Klein,Naël Osmani,Ignacio Busnelli,François Delalande,Nicodème Paul,Sébastien Halary,Frédéric Gros,Laetitia Fouillen,Anne-Marie Haeberlé,Catherine A. Royer,Coralie Spiegelhalter,Gwennan André-Grégoire,Kendelle J. Murphy,Kendelle J. Murphy,Paul Timpson,Paul Timpson,Raphael Carapito,Marcel Blot-Chabaud,Julie Gavard,Christine Carapito,Nicolas Vitale,Olivier Lefebvre,Jacky G. Goetz,Vincent Hyenne +26 more
TL;DR: It is shown that GTPases of the Ral family control, through the phospholipase D1, multi-vesicular bodies homeostasis and thereby tune the biogenesis and secretion of pro-metastatic EVs.