Benjamin R. Capraro

TL;DR: The present review first provides an overview of important classes of membrane proteins for which function is coupled to membrane curvature, and surveys several mechanisms that are assumed to underlie membranes curvature sensing and generation.

TL;DR: It is demonstrated that Exo70, a component of the exocyst complex, induces tubular membrane invaginations toward the lumen of synthetic vesicles in vitro and generates protrusions on the surface of cells.

TL;DR: The results highlight the possibility that epsin contributes to cellular membrane curvature sensing and generation, and believe that the method will provide useful contributions toward the goal of relating molecular descriptions of interactions to macroscopic membrane remodeling in cells and identifying and characterizing roles for proteins in these processes.

TL;DR: It is demonstrated that the stiffness of ternary lipid mixtures depends on membrane curvature for a large range of lipid compositions, and that curvature-induced demixing increases upon approaching the critical region of a ternARY lipid mixture.

TL;DR: A wavy substrate is fabricated by imposing a range of curvatures onto an adhering lipid bilayer membrane to examine the curvature sorting of several peripheral proteins binding to the wavy membrane and suggest that the curvatures sensing of proteins on low-curvature substrates requires cooperative interactions.