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Bernard Chow
Researcher at Genentech
Publications - 4
Citations - 766
Bernard Chow is an academic researcher from Genentech. The author has contributed to research in topics: Protein sequencing & Exome. The author has an hindex of 4, co-authored 4 publications receiving 699 citations.
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Journal ArticleDOI
The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment
Hilary Clark,Austin L. Gurney,Evangeline Abaya,Kevin P. Baker,Daryl T. Baldwin,Jennifer Brush,Jian Chen,Bernard Chow,Clarissa Chui,Craig Crowley,Bridget Currell,Bethanne Deuel,Patrick Dowd,Dan L. Eaton,Jessica Foster,Christopher Grimaldi,Qimin Gu,Philip E. Hass,Sherry Heldens,Arthur J Huang,Hok Seon Kim,Laura Klimowski,Yisheng Jin,Stephanie Johnson,James Lee,Lhney Lewis,Dongzhou Liao,Melanie R. Mark,Edward P. Robbie,Celina Sanchez,Jill Schoenfeld,Somasekar Seshagiri,Laura Simmons,Jennifer Singh,Victoria Smith,Jeremy Stinson,Alicia Vagts,Richard Vandlen,Colin K. Watanabe,David Wieand,Kathryn Woods,Ming-Hong Xie,Daniel G. Yansura,Sothy Yi,Guoying Yu,Jean Yuan,Min Zhang,Zemin Zhang,Audrey Goddard,William I. Wood,Paul J. Godowski +50 more
TL;DR: The SPDI collection should facilitate efforts to better understand intercellular communication, may lead to new understandings of human diseases, and provides potential opportunities for the development of therapeutics.
Journal ArticleDOI
Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.
Steffen Durinck,Eric Stawiski,Andrea Pavia-Jimenez,Zora Modrusan,Payal Kapur,Bijay S. Jaiswal,Na Zhang,Vanina Toffessi-Tcheuyap,Thong T. Nguyen,Kanika Bajaj Pahuja,Ying Jiun Chen,Sadia Saleem,Subhra Chaudhuri,Sherry Heldens,Marlena Jackson,Samuel Peña-Llopis,Joseph Guillory,Karen Toy,Connie Ha,Corissa J. Harris,Eboni Holloman,Haley Hill,Jeremy Stinson,Celina Sanchez Rivers,Vasantharajan Janakiraman,Weiru Wang,Lisa N. Kinch,Lisa N. Kinch,Nick V. Grishin,Peter M. Haverty,Bernard Chow,Julian S. Gehring,Jens Reeder,Gregoire Pau,Thomas D. Wu,Vitaly Margulis,Yair Lotan,Arthur I. Sagalowsky,Ivan Pedrosa,Frederic J. de Sauvage,James Brugarolas,Somasekar Seshagiri +41 more
TL;DR: Gene expression analysis identified a five-gene set that enabled the molecular classification of chRCC, renal oncocytoma and pRCC and observed upregulation of the anti-apoptotic factor BIRC7 in MiTF-high RCC tumors, suggesting a potential therapeutic role for BIRC 7 inhibitors.
Journal ArticleDOI
A rapid method for estimation of baculovirus titer based on viable cell size.
TL;DR: A simple and rapid method for determination of virus titers based on the cytopathic effects that lead to viable cell size increase following virus infection is presented and indicated that the viable cell-diameter based titer estimation to be reliable and comparable to titers determined by the traditional plaque assay.
Journal ArticleDOI
Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection.
Brock A. Peters,Zhengyan Kan,Dragan Sebisanovic,Kanan Pujara,Zhiyong Wang,Peter Hong,Bernard Chow,Jeremy Stinson,Victoria Carlton,Thinh Pham,Howard M. Stern,Paul Waring,Kenneth J. Hillan,David A. Eberhard,Frederic J. de Sauvage,Jianbiao Zheng,Malek Faham,Somasekar Seshagiri +17 more
TL;DR: The results showed that MRD is a robust and cost-effective alternative to Sanger sequencing for identifying somatic mutations in human tumors.