B
Bertram Wiedenmann
Researcher at Charité
Publications - 571
Citations - 40861
Bertram Wiedenmann is an academic researcher from Charité. The author has contributed to research in topics: Neuroendocrine tumors & Synaptophysin. The author has an hindex of 97, co-authored 560 publications receiving 37833 citations. Previous affiliations of Bertram Wiedenmann include Rush University Medical Center & Heidelberg University.
Papers
More filters
Journal ArticleDOI
Sunitinib malate for the treatment of pancreatic neuroendocrine tumors.
Eric Raymond,Laetitia Dahan,Jean-Luc Raoul,Yung-Jue Bang,Ivan Borbath,Catherine Lombard-Bohas,Juan W. Valle,Peter Metrakos,Denis Smith,Aaron I. Vinik,Jen-Shi Chen,Dieter Hörsch,Pascal Hammel,Bertram Wiedenmann,Eric Van Cutsem,Shem Patyna,Dongrui Ray Lu,C. Blanckmeister,Richard C. Chao,Philippe Ruszniewski +19 more
TL;DR: Continuous daily administration of sunitinib at a dose of 37.5 mg improved progression-free survival, overall survival, and the objective response rate as compared with placebo among patients with advanced pancreatic neuroendocrine tumors.
Journal ArticleDOI
TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system
Guido Rindi,Günter Klöppel,H. Alhman,Martyn Caplin,Anne Couvelard,W. W. de Herder,B. Erikssson,Alberto Falchetti,Massimo Falconi,P. Komminoth,Meike Körner,José Manuel Lopes,A-M. McNicol,Ola Nilsson,Aurel Perren,Aldo Scarpa,J.-Y. Scoazec,Bertram Wiedenmann +17 more
TL;DR: The tumor–node–metastasis proposal for foregut NETs of the stomach, duodenum, and pancreas that was designed, discussed, and consensually approved at this conference is reported.
Journal ArticleDOI
Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles.
TL;DR: A polypeptide of Mr 38,000 has been identified as a specific component of the membrane of presynaptic vesicles, using the monoclonal antibody SY38, and this protein, for which the name synaptophysin*, is proposed, provides a molecular marker for the presyspheric membrane and may be involved in synaptic vesicle formation and exocytosis.
Journal ArticleDOI
TNM staging of midgut and hindgut (neuro) endocrine tumors: a consensus proposal including a grading system
Guido Rindi,Günter Klöppel,Anne Couvelard,P. Komminoth,Meike Körner,José Manuel Lopes,Anne Marie McNicol,Ola Nilsson,Aurel Perren,Aldo Scarpa,J.-Y. Scoazec,Bertram Wiedenmann +11 more
TL;DR: The proposed tumor–node–metastasis (TNM) classifications are based on the recently published ENETS Guidelines for the Diagnosis and Treatment of gastroenteropancreatic NETs and follow the previous proposal for foregut tumors.
Journal ArticleDOI
A colorectal cancer classification system that associates cellular phenotype and responses to therapy
Anguraj Sadanandam,Costas A. Lyssiotis,Costas A. Lyssiotis,Krisztian Homicsko,Krisztian Homicsko,Eric A. Collisson,William J. Gibb,Stephan Wullschleger,Liliane C Gonzalez Ostos,William A Lannon,William A Lannon,Carsten Grötzinger,Maguy Del Rio,Benoit Lhermitte,Adam B. Olshen,Bertram Wiedenmann,Lewis C. Cantley,Lewis C. Cantley,Joe W. Gray,Douglas Hanahan +19 more
TL;DR: Three subtypes have markedly better disease-free survival (DFS) after surgical resection, suggesting these patients might be spared from the adverse effects of chemotherapy when they have localized disease.