M
Maguy Del Rio
Researcher at French Institute of Health and Medical Research
Publications - 39
Citations - 3607
Maguy Del Rio is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Colorectal cancer & Irinotecan. The author has an hindex of 20, co-authored 34 publications receiving 3170 citations. Previous affiliations of Maguy Del Rio include Centre national de la recherche scientifique & University of Montpellier.
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Journal ArticleDOI
A colorectal cancer classification system that associates cellular phenotype and responses to therapy
Anguraj Sadanandam,Costas A. Lyssiotis,Costas A. Lyssiotis,Krisztian Homicsko,Krisztian Homicsko,Eric A. Collisson,William J. Gibb,Stephan Wullschleger,Liliane C Gonzalez Ostos,William A Lannon,William A Lannon,Carsten Grötzinger,Maguy Del Rio,Benoit Lhermitte,Adam B. Olshen,Bertram Wiedenmann,Lewis C. Cantley,Lewis C. Cantley,Joe W. Gray,Douglas Hanahan +19 more
TL;DR: Three subtypes have markedly better disease-free survival (DFS) after surgical resection, suggesting these patients might be spared from the adverse effects of chemotherapy when they have localized disease.
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Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA
Alain R. Thierry,Florent Mouliere,Safia El Messaoudi,Caroline Mollevi,Evelyne Lopez-Crapez,Fanny Rolet,Brigitte Gillet,Céline Gongora,Pierre Déchelotte,Bruno Robert,Maguy Del Rio,Pierre-Jean Lamy,Frédéric Bibeau,Michelle Nouaille,Virginie Loriot,Anne Sophie Jarrousse,Franck Molina,Muriel Mathonnet,Denis Pezet,Marc Ychou +19 more
TL;DR: This study shows that liquid biopsy through cfDNA analysis could advantageously replace tumor-section analysis and expand the scope of personalized medicine for patients with cancer.
Journal ArticleDOI
High Fragmentation Characterizes Tumour-Derived Circulating DNA
Florent Mouliere,Bruno Robert,Erika Arnau Peyrotte,Maguy Del Rio,Marc Ychou,Franck Molina,Céline Gongora,Alain R. Thierry +7 more
TL;DR: Q-PCR analysis of plasma samples from xenografted mice and cancer patients showed that tumour-derived ct DNA exhibits a specific amount profile based on ctDNA size and significant higher cTDNA fragmentation.
Journal ArticleDOI
Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts
Alain R. Thierry,Florent Mouliere,Céline Gongora,Jeremy Ollier,Bruno Robert,Marc Ychou,Maguy Del Rio,Franck Molina +7 more
TL;DR: The results suggest that ctDNA features vary during CRC tumor development and an experimental system to systematically examine these aspects might be a useful tool to follow such variations.
Journal ArticleDOI
Impact of RNA degradation on gene expression profiles : Assessment of different methods to reliably determine RNA quality
Virginie Copois,Frédéric Bibeau,Caroline Bascoul-Mollevi,Nicolas Salvetat,Patrick Chalbos,C. Bareil,Laurent Candeil,Caroline Fraslon,Emmanuel Conseiller,Virginie Granci,Pierre Mazière,Andrew Kramar,Marc Ychou,Bernard Pau,Pierre Martineau,Franck Molina,Maguy Del Rio +16 more
TL;DR: A new approach, based on clustering analyses of full chip expression, to control RNA quality after hybridization experiments, ensured reliable and reproducible microarray data.