B
Binbin Chen
Researcher at Stanford University
Publications - 26
Citations - 3276
Binbin Chen is an academic researcher from Stanford University. The author has contributed to research in topics: Cancer & Biology. The author has an hindex of 12, co-authored 22 publications receiving 1519 citations. Previous affiliations of Binbin Chen include National Institutes of Health & Georgia Institute of Technology.
Papers
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Book ChapterDOI
Profiling Tumor Infiltrating Immune Cells with CIBERSORT
TL;DR: A primer on the CIBERSORT method is provided and its use for characterizing TILs in tumor samples profiled by microarray or RNA-Seq is illustrated.
Journal ArticleDOI
Integrating genomic features for non-invasive early lung cancer detection
Jacob J. Chabon,Emily G. Hamilton,David M. Kurtz,Mohammad Shahrokh Esfahani,Everett J. Moding,Henning Stehr,Joseph G Schroers-Martin,Barzin Y. Nabet,Binbin Chen,Aadel A. Chaudhuri,Chih Long Liu,Angela B. Hui,Michael C. Jin,Tej D. Azad,Diego Almanza,Young-Jun Jeon,Monica Nesselbush,Lyron Co Ting Keh,Rene F. Bonilla,Christopher H. Yoo,Ryan B. Ko,Emily Chen,D.J. Merriott,Pierre P. Massion,Pierre P. Massion,Aaron S. Mansfield,Jin Jen,Hong Z. Ren,Steven H. Lin,Christina L. Costantino,Risa Burr,Risa Burr,Robert Tibshirani,Sanjiv S. Gambhir,Gerald J. Berry,Kristin C. Jensen,Kristin C. Jensen,Robert B. West,Joel W. Neal,Heather A. Wakelee,Billy W. Loo,Christian A. Kunder,Ann N. Leung,Natalie S. Lui,Mark F. Berry,Joseph B. Shrager,Joseph B. Shrager,Viswam S. Nair,Viswam S. Nair,Viswam S. Nair,Daniel A. Haber,Daniel A. Haber,Lecia V. Sequist,Ash A. Alizadeh,Maximilian Diehn +54 more
TL;DR: It is shown that, although levels are very low in early-stage lung cancers, ctDNA is present prior to treatment in most patients and its presence is strongly prognostic, and a machine-learning method termed ‘lung cancer likelihood in plasma’ (Lung-CLiP) is developed, which can robustly discriminate early-Stage lung cancer patients from risk-matched controls.
Proceedings ArticleDOI
Empath: Understanding Topic Signals in Large-Scale Text
TL;DR: Empath is a tool that can generate and validate new lexical categories on demand from a small set of seed terms, which draws connotations between words and phrases by deep learning a neural embedding across more than 1.8 billion words of modern fiction.
Proceedings ArticleDOI
Empath: Understanding Topic Signals in Large-Scale Text
TL;DR: Emppath as mentioned in this paper is a tool that can generate and validate new lexical categories on demand from a small set of seed terms (like "bleed" and "punch" to generate the category violence).
Journal ArticleDOI
Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens
Michael S. Khodadoust,Niclas Olsson,Lisa E. Wagar,Ole Audun Werner Haabeth,Binbin Chen,Kavya Swaminathan,Keith Rawson,Chih Long Liu,David F. Steiner,Peder Lund,Samhita Rao,Lichao Zhang,Caleb D. Marceau,Henning Stehr,Aaron M. Newman,Debra K. Czerwinski,Victoria Carlton,Martin Moorhead,Malek Faham,Holbrook E Kohrt,Jan E. Carette,Michael R. Green,Mark M. Davis,Ronald Levy,Joshua E. Elias,Ash A. Alizadeh +25 more
TL;DR: This work discovers neoantigens in human mantle-cell lymphomas by using an integrated genomic and proteomic strategy that interrogates tumour antigen peptides presented by major histocompatibility complex (MHC) class I and class II molecules.