Bing Huey

TL;DR: The arrays provide precise measurement in cell lines and clinical material, so that they can reliably detect and quantify high-level amplifications and single-copy alterations in diploid, polyploid and heterogeneous backgrounds.

TL;DR: P phenotypically normal mammary epithelial cells with tetracycline-regulated expression of MMP3/stromelysin-1 (Str1) form epithelial glandular structures in vivo without Str1 but form invasive mesenchymal-like tumors with Str1, indicating that Str1 influences tumor initiation and alters neoplastic risk.

TL;DR: In this article, the authors investigated changes in the microbiome associated with oral cancers, profiled cancers and anatomically matched contralateral normal tissue from the same patient by sequencing 16S rDNA hypervariable region amplicons.

TL;DR: It is shown that small ratio changes distinguish homozygous and heterozygous regions of the genome in interspecific backcross mice, providing an efficient method for genotyping progeny of backcrosses.

TL;DR: The results in chest skin were complex in that the severity of chest precursors diminished, but their incidence was unchanged, and microscopic cancers were still detectable within these lesions, which highlights the utility of multistage epidermal carcinogenesis in K14-HPV16 transgenic mice.