Bishal Gyawali

TL;DR: The analysis of 33 health-related SDG indicators based on the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 highlights the importance of income, education, and fertility as drivers of health improvement but also emphasises that investments in these areas alone will not be sufficient.

TL;DR: In this paper, the authors describe phases of early detection program development, beginning with management strategies required for the diagnosis of clinically detectable disease based on awareness education and technical training, history and physical examination, and accurate tissue diagnosis, and highlight the challenges and opportunities of implementing successful breast cancer early detection programs, and the complex interplay of barriers and facilitators to achieving early detection for breast cancer in real world settings are considered.

TL;DR: Confirmatory trials for one-fifth of cancer drug indications approved via the FDA's accelerated approval pathway demonstrated improvements in overall patient survival, and update the outcomes of accelerated approvals with confirmatory trials that were ongoing at the time of FDA's review.

TL;DR: A variable prevalence of hypertension is found across SAARC countries, with a number of countries with blood pressure above the global average, and studies are not consistent in their data collection about hypertension and related modifiable risk factors.

TL;DR: It is shown that HDT/ASCT was associated with superior PFS with minimal toxic effects compared with SDT, and longer follow-up may better delineate any OS benefit; however, is likely to be affected by effective postrelapse therapy.