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Björn O. Forsberg
Researcher at Science for Life Laboratory
Publications - 22
Citations - 5889
Björn O. Forsberg is an academic researcher from Science for Life Laboratory. The author has contributed to research in topics: GLIC & Ion channel. The author has an hindex of 10, co-authored 20 publications receiving 3307 citations. Previous affiliations of Björn O. Forsberg include Max Planck Society & Stockholm University.
Papers
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Journal ArticleDOI
New tools for automated high-resolution cryo-EM structure determination in RELION-3.
Jasenko Zivanov,Takanori Nakane,Björn O. Forsberg,Dari Kimanius,Wim J. H. Hagen,Erik Lindahl,Erik Lindahl,Sjors H.W. Scheres +7 more
TL;DR: CPU-based vector acceleration has been added in addition to GPU support, which provides flexibility in use of resources and avoids memory limitations in the third major release of RELION.
Peer ReviewDOI
Author response: New tools for automated high-resolution cryo-EM structure determination in RELION-3
Jasenko Zivanov,Takanori Nakane,Björn O. Forsberg,Dari Kimanius,Wim J. H. Hagen,Erik Lindahl,Erik Lindahl,Sjors H.W. Scheres +7 more
Journal ArticleDOI
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
TL;DR: An implementation of the RELION image processing software that uses graphics processors (GPUs) to address the most computationally intensive steps of its cryo-EM structure determination workflow, and it is shown that the use of single precision arithmetic does not adversely affect results.
Journal ArticleDOI
Crystal Structure and Functional Mechanism of a Human Antimicrobial Membrane Channel.
Chen Song,Conrad Weichbrodt,Evgeniy S. Salnikov,Marek Dynowski,Björn O. Forsberg,Burkhard Bechinger,Claudia Steinem,Bert L. de Groot,Ulrich Zachariae,Kornelius Zeth,Kornelius Zeth +10 more
TL;DR: In this paper, the authors presented the X-ray crystal structure as well as solid-state NMR spectroscopy, electrophysiology, and MD simulations of human dermcidin in membranes that reveal the antibiotic mechanism of this major human antimicrobial, found to suppress Staphylococcus aureus growth on the epidermal surface.
Posted ContentDOI
RELION-3: new tools for automated high-resolution cryo-EM structure determination
Jasenko Zivanov,Takanori Nakane,Björn O. Forsberg,Dari Kimanius,Wim J. H. Hagen,Erik Lindahl,Sjors H.W. Scheres +6 more
TL;DR: The third major release of RELION as mentioned in this paper has been added in addition to GPU support, which provides flexibility in use of resources and avoids memory limitations Reference-free autopicking with Laplacian-of-Gaussian filtering and execution of jobs from python allows non-interactive processing during acquisition, including 2D-classification, de novo model generation and 3D classification Per-particle refinement of CTF parameters and correction of estimated beam tilt provides higher-resolution reconstructions when particles are at different heights in the ice, and/or coma-free alignment has not