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Anna C. Shore
Researcher at Trinity College, Dublin
Publications - 62
Citations - 3786
Anna C. Shore is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: SCCmec & Methicillin-resistant Staphylococcus aureus. The author has an hindex of 29, co-authored 61 publications receiving 3343 citations. Previous affiliations of Anna C. Shore include University College Dublin.
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Journal ArticleDOI
A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus
Stefan Monecke,Geoffrey W. Coombs,Anna C. Shore,David C. Coleman,Patrick Eberechi Akpaka,Michael Borg,Henry Chow,Margaret Ip,Lutz Jatzwauk,Daniel Jonas,Kristina Kadlec,Angela M. Kearns,Frédéric Laurent,Frances G. O'Brien,Julie C. Pearson,Antje Ruppelt,Stefan Schwarz,E. Scicluna,Peter Slickers,Hui-Leen Tan,Stefan Weber,Ralf Ehricht +21 more
TL;DR: A high level of biodiversity among MRSA, especially among strains harbouring SCCmec IV and V elements is shown, and the data indicate a high rate of genetic recombination in MRSA involving SCC elements, bacteriophages or other mobile genetic elements and large-scale chromosomal replacements.
Journal ArticleDOI
Detection of Staphylococcal Cassette Chromosome mec Type XI Carrying Highly Divergent mecA, mecI, mecR1, blaZ, and ccr Genes in Human Clinical Isolates of Clonal Complex 130 Methicillin-Resistant Staphylococcus aureus
Anna C. Shore,E.C. Deasy,Peter Slickers,Gráinne I. Brennan,Brian O'Connell,Stefan Monecke,Ralf Ehricht,David C. Coleman +7 more
TL;DR: Two clonal complex 130 methicillin-resistant Staphylococcus aureus isolates from patients in Irish hospitals were identified that were phenotypically PBP 2a positive but lacked mecA by conventional PCR and by DNA microarray screening, suggesting they may have originated in another taxon.
Journal ArticleDOI
Seven novel variants of the staphylococcal chromosomal cassette mec in methicillin-resistant Staphylococcus aureus isolates from Ireland.
TL;DR: This study has demonstrated a hitherto-undescribed degree of diversity within SCCmec, and revealed that 129/130 isolates had the same genotypes as internationally spread MRSA clones.
Journal ArticleDOI
The Emergence and Importation of Diverse Genotypes of Methicillin-Resistant Staphylococcus aureus (MRSA) Harboring the Panton-Valentine Leukocidin Gene (pvl) Reveal that pvl Is a Poor Marker for Community-Acquired MRSA Strains in Ireland
Angela S. Rossney,Anna C. Shore,Pamela M. Morgan,MM Fitzgibbon,Brian O'Connell,David C. Coleman +5 more
TL;DR: It is demonstrated that pvl is not a reliable marker for CA-MRSA in Ireland and reveals the emergence and importation of diverse genotypes of pvl-positive MRSA inIreland.
Journal ArticleDOI
Staphylococcal cassette chromosome mec: recent advances and new insights.
Anna C. Shore,David C. Coleman +1 more
TL;DR: Detailed characterisation of SCC and SCCmec elements and CIs represents a unique challenge but is vital for effective epidemiological typing and tracking of MRSA and other staphylococci and to enhance the understanding of the origins and evolution ofMRSA.