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Bruce Albala
Researcher at University of California, Irvine
Publications - 44
Citations - 2381
Bruce Albala is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Epilepsy & Medicine. The author has an hindex of 21, co-authored 40 publications receiving 1979 citations. Previous affiliations of Bruce Albala include Albert Einstein College of Medicine & Yeshiva University.
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Journal ArticleDOI
Kainic-acid-induced seizures: a developmental study.
TL;DR: The results suggest that the lack of substantia nigra involvement in the pups may account for the early generalization and the increased severity of seizures in this age group.
Journal ArticleDOI
The β-Secretase BACE1 in Alzheimer's Disease.
Harald Hampel,Robert Vassar,Bart De Strooper,Bart De Strooper,Bart De Strooper,John Hardy,Michael Willem,Neeraj Kumar Singh,John Zhou,Riqiang Yan,Eugeen Vanmechelen,Ann De Vos,Robert Nisticò,Massimo Corbo,Bruno P. Imbimbo,Johannes Streffer,Iryna Voytyuk,Iryna Voytyuk,Iryna Voytyuk,Maarten Timmers,Maarten Timmers,Amir Abbas Tahami Monfared,Amir Abbas Tahami Monfared,Michael C. Irizarry,Bruce Albala,Akihiko Koyama,Naoto Watanabe,Teiji Kimura,Lisa Yarenis,Simone Lista,Simone Lista,Lynn D. Kramer,Andrea Vergallo +32 more
TL;DR: BACE1 concentrations and rates of activity are increased in AD brains and body fluids, thereby supporting the hypothesis that BACE1 plays a critical role in AD pathophysiology, and is a prime drug target for slowing down Aβ production in early AD.
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Comparative effects of nefazodone and fluoxetine on sleep in outpatients with major depressive disorder
A. John Rush,Roseanne Armitage,J. Christian Gillin,J. Christian Gillin,Kimberly A. Yonkers,Andrew Winokur,Harvey Moldofsky,Gerald W. Vogel,Stephen Kaplita,Jonathan B Fleming,Jacques Montplaisir,Milton K. Erman,Bruce Albala,Robert D. McQuade +13 more
TL;DR: Nefazodone was associated with normal objective, and clinician- and patient-rated assessments of sleep when compared with fluoxetine, and these differential sleep EEG effects are consistent with the notion that nefzodone and fluoxettine may have somewhat different modes and spectra of action.
Journal ArticleDOI
Increased seizure susceptibility of the immature brain.
TL;DR: The data suggest that seizure susceptibility changes with age and is greater early in life, and that short (less than 15 min) seizure refractory periods exist in the immature brain.
Journal ArticleDOI
Detecting cognitive changes in preclinical Alzheimer's disease: A review of its feasibility.
Marion Mortamais,Marion Mortamais,Jessica A. Ash,John Harrison,Jeffrey Kaye,Joel H. Kramer,Christopher Randolph,Carine Pose,Bruce Albala,Michael T. Ropacki,Craig W. Ritchie,Karen Ritchie,Karen Ritchie,Karen Ritchie +13 more
TL;DR: Prospective studies point to early decline in both episodic and semantic memory processing as well as executive functions in the predementia period, and new procedures are required which target more finely the medial temporal lobe subregions first affected by clinically silent AD pathology.