Bruce Patterson

TL;DR: Lymphocyte-specific interferon regulatory factor (LSIRF) (now called IRF4) is a transcription factor expressed only in lymphocytes that is essential for the function and homeostasis of both mature B and mature T lymphocytes.

TL;DR: The expression of 950 genes in Hodgkin's disease (HD) is investigated by analyzing differential mRNA expression using microarrays and suggests that IL-13 plays an important role in the stimulation of H/RS cell growth, possibly by an autocrine mechanism.

TL;DR: No clear evidence has shown that early treatment of isolated chloroma with chemotherapy alters progression to leukemia or prolongs survival, and to address this issue, an analysis of a comprehensive retrospective review of the medical literature was conducted.

TL;DR: Novel in vivo evidence is provided that caspase-3, conventionally known for its downstream effector function in apoptosis, also modifies Bcl-2 and other upstream proteins involved in the regulation of Fas-mediated apoptosis.

TL;DR: There is currently no evidence that other products are safer than Ab+ PRCA, and the subcutaneous administration of HSA-containing Eprex is riskier than intravenous Epogen and intravenous HSA/subcutaneous NeoRecormon is riskiest than intravenously Epogen.