B
Bryan R. Cullen
Researcher at Duke University
Publications - 376
Citations - 52946
Bryan R. Cullen is an academic researcher from Duke University. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 121, co-authored 371 publications receiving 50901 citations. Previous affiliations of Bryan R. Cullen include Hoffmann-La Roche & University of Medicine and Dentistry of New Jersey.
Papers
More filters
Journal ArticleDOI
Five Questions about Viruses and MicroRNAs
TL;DR: The primary, and possibly sole, function of mammalian miRNAs is to act as specific post-transcriptional inhibitors of mRNA function.
Journal ArticleDOI
A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses
TL;DR: The hypothesis that these special RNA folding regions are functionally important and suggest that the role of this sequence as the Rev response element (RRE) is mediated by secondary structure as well as primary RNA sequence are supported.
Journal ArticleDOI
The role of Nef in the replication cycle of the human and simian immunodeficiency viruses.
Journal ArticleDOI
Induction of stable RNA interference in mammalian cells
TL;DR: A set of design criteria, experimental steps and expression vectors that can facilitate the effective knock-down of almost any vertebrate gene product in cultured cells or in experimental animals are described.
Journal ArticleDOI
Efficient polyadenylation within the human immunodeficiency virus type 1 long terminal repeat requires flanking U3-specific sequences.
TL;DR: Experiments are described that suggest that transcribed sequences present within the human immunodeficiency virus type 1 LTR U3 region act in cis to enhance polyadenylation within the 3' LTR.