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Bryan R. Cullen
Researcher at Duke University
Publications - 376
Citations - 52946
Bryan R. Cullen is an academic researcher from Duke University. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 121, co-authored 371 publications receiving 50901 citations. Previous affiliations of Bryan R. Cullen include Hoffmann-La Roche & University of Medicine and Dentistry of New Jersey.
Papers
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Journal ArticleDOI
Regulatory pathways governing HIV-1 replication
Bryan R. Cullen,Warner C. Greene +1 more
Journal ArticleDOI
The peripheral myelin protein gene PMP-22 is contained within the Charcot-Marie-Tooth disease type 1A duplication.
Vincent Timmerman,Eva Nelis,W. Van Hui,Bart W. Nieuwenhuijsen,K.L. Chen,S. Wang,K. Ben Othman,Bryan R. Cullen,Robin J. Leach,Clemens Oliver Hanemann,P. De Jonghe,Peter Raeymaekers,G.J.B. van Ommen,J. J. Martin,Hans Werner Müller,Jeffery M. Vance,Kenneth H. Fischbeck,C. Van Broeckhoven +17 more
TL;DR: It is suggested that increased dosage of the PMP–22 gene may be the cause of CMT1A neuropathy.
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Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes.
TL;DR: The results suggest that normal nonproliferating mononuclear phagocytes, which are relatively resistant to the destructive effects of this virus, may serve as persistent and productive reservoirs for HIV-1 in vivo.
Journal ArticleDOI
Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis.
Shihua Lu,Bryan R. Cullen +1 more
TL;DR: Evidence is presented demonstrating that the highly structured ∼160-nucleotide adenoviral VA1 noncoding RNA can inhibit RNAi at physiological levels of expression and identifying VA1 RNA as the first viral gene product able to inhibitRNAi in human cells.
Journal ArticleDOI
Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.
Hal P. Bogerd,Heather L. Wiegand,Amy E. Hulme,Jose L. Garcia-Perez,K. Sue O'Shea,John V. Moran,Bryan R. Cullen +6 more
TL;DR: The data suggest that the APOBEC3 protein family may have evolved, at least in part, to defend the integrity of the human genome against endogenous retrotransposons.