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Bryan R. Cullen
Researcher at Duke University
Publications - 376
Citations - 52946
Bryan R. Cullen is an academic researcher from Duke University. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 121, co-authored 371 publications receiving 50901 citations. Previous affiliations of Bryan R. Cullen include Hoffmann-La Roche & University of Medicine and Dentistry of New Jersey.
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Journal ArticleDOI
Nuclear RNA Export Pathways
TL;DR: This review will describe the mechanisms used by the cell to move different classes of cellular RNA from their nuclear site of synthesis to the cytoplasm, where the majority then participate in the process of protein synthesis.
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COOH-terminal requirements for the correct processing of a phosphatidylinositol-glycan anchored membrane protein.
TL;DR: It was found that to be PI-G-tailed the newly synthesized protein must possess an uncharged, predominantly hydrophobic amino acid sequence of a minimal length in the COOH-terminal peptide.
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Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species
TL;DR: It is demonstrated that HIV-2 and SIVmac also encode functional Rev proteins, which may imply a direct role for Rev in mediating the recognition of its viral RNA target sequence.
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Differential RISC association of endogenous human microRNAs predicts their inhibitory potential
TL;DR: It is demonstrated that endogenous human miRNAs vary widely in their level of RISC association and it is shown that the level of Ago binding is a better indicator of inhibitory potential than is the total level of miRNA expression.