Byrappa Venkatesh

TL;DR: The characterization of the relatively small genome of a cartilaginous fish, the elephant fish, is reported, and it is proposed as a model for whole-genome sequencing.

TL;DR: In this article, the role of Ikaros binding elements in the human STAT4 promoter using Jurkat T cells was investigated, and it was shown that Ik is involved in the regulation of STAT4 in human T cells.

TL;DR: Cloned and sequenced the teleost homologs of the human genes encoding platelet-derived growth factor receptor-beta (PDGFR beta) and macrophage colony-stimulating factor 1 receptor (CSFIR) from the puffer fish Fugu rubripes revealed several short stretches of conserved sequences that may have a role in the regulation of expression of either or both of these closely linked genes.

TL;DR: An international project known as the “Transcriptomes of 1,000 Fishes” (Fish-T1K) project has been established to generate RNA-seq transcriptome sequences for 1, thousand diverse species of ray-finned fishes.

TL;DR: For instance, this paper found that non-CpG methylation plays a critical regulatory role in cognitive function, which is mediated by the binding of MeCP2, the transcriptional regulator that when mutated causes Rett syndrome.