A
Alice Tay
Researcher at Agency for Science, Technology and Research
Publications - 19
Citations - 3458
Alice Tay is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 15, co-authored 19 publications receiving 3272 citations. Previous affiliations of Alice Tay include Institute of Molecular and Cell Biology.
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Journal ArticleDOI
Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes
Samuel Aparicio,Jarrod Chapman,Elia Stupka,Nik Putnam,Jer Ming Chia,Paramvir S. Dehal,Alan Christoffels,Sam Rash,Shawn Hoon,Arian F.A. Smit,Maarten D. Sollewijn Gelpke,Jared C. Roach,Tania Oh,Isaac Ho,Marie Wong,Chris Detter,Frans Verhoef,Paul Predki,Alice Tay,Susan Lucas,Paul G. Richardson,Sarah Smith,Melody S. Clark,Yvonne J. K. Edwards,Norman A. Doggett,Andrey Zharkikh,Sean V. Tavtigian,Dmitry Pruss,Mary Barnstead,Cheryl Evans,Holly Baden,Justin Powell,Gustavo Glusman,Lee Rowen,Leroy Hood,Y. H. Tan,Greg Elgar,Trevor Hawkins,Byrappa Venkatesh,Daniel S. Rokhsar,Sydney Brenner +40 more
TL;DR: The Fugu rubripes genome has been sequenced to over 95% coverage, and more than 80% of the assembly is in multigene-sized scaffolds as discussed by the authors.
Journal ArticleDOI
Elephant shark genome provides unique insights into gnathostome evolution
Byrappa Venkatesh,Byrappa Venkatesh,Alison P. Lee,Vydianathan Ravi,Ashish K. Maurya,Michelle M. Lian,Jeremy B. Swann,Yuko Ohta,Martin F. Flajnik,Yoichi Sutoh,Masanori Kasahara,Shawn Hoon,Vamshidhar Gangu,Scott William Roy,Manuel Irimia,Vladimir Korzh,Igor Kondrychyn,Zhi Wei Lim,Boon Hui Tay,Sumanty Tohari,Kiat Whye Kong,Shufen Ho,Belen Lorente-Galdos,Belen Lorente-Galdos,Javier Quilez,Javier Quilez,Tomas Marques-Bonet,Tomas Marques-Bonet,Brian J. Raney,Philip W. Ingham,Alice Tay,LaDeana W. Hillier,Patrick Minx,Thomas Boehm,Richard K. Wilson,Sydney Brenner,Wesley C. Warren +36 more
TL;DR: The whole-genome analysis of a cartilaginous fish, the elephant shark (Callorhinchus milii), finds that the C. milii genome is the slowest evolving of all known vertebrates, and features extensive synteny conservation with tetrapod genomes, making it a good model for comparative analyses of gnathostome genomes.
Journal ArticleDOI
Survey sequencing and comparative analysis of the elephant shark (Callorhinchus milii) genome.
Byrappa Venkatesh,Ewen F. Kirkness,Yong-Hwee E. Loh,Aaron L. Halpern,Alison P. Lee,Justin Johnson,Nidhi Dandona,Lakshmi D. Viswanathan,Alice Tay,J. Craig Venter,Robert L. Strausberg,Sydney Brenner +11 more
TL;DR: Survey sequencing and comparative analysis of the elephant shark genome are described, showing the degree of conserved synteny and conserved sequences between the human and elephant shark genomes are higher than that between human and teleost fish genomes.
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Evidence for at least six Hox clusters in the Japanese lamprey (Lethenteron japonicum)
Tarang K. Mehta,Tarang K. Mehta,Vydianathan Ravi,Shinichi Yamasaki,Alison P. Lee,Michelle M. Lian,Boon-Hui Tay,Sumanty Tohari,Seiji Yanai,Alice Tay,Sydney Brenner,Sydney Brenner,Byrappa Venkatesh,Byrappa Venkatesh +13 more
TL;DR: Lampreys and hagfishes (cyclostomes) are the only living group of jawless vertebrates and therefore are important for the study of vertebrate evolution, and characterized Hox clusters in the Japanese lamprey (Lethenteron japonicum) has been characterized, suggesting that the lamprey lineage has undergone an additional round of genome duplication compared with tetrapods.
Journal ArticleDOI
Integration of the Genetic Map and Genome Assembly of Fugu Facilitates Insights into Distinct Features of Genome Evolution in Teleosts and Mammals
Wataru Kai,Kiyoshi Kikuchi,Sumanty Tohari,Ah Keng Chew,Alice Tay,Atushi Fujiwara,Sho Hosoya,Hiroaki Suetake,Kiyoshi Naruse,Sydney Brenner,Yuzuru Suzuki,Byrappa Venkatesh +11 more
TL;DR: The consolidated genome map and the genetic map of fugu are valuable resources for comparative genomics of vertebrates and for elucidating the genetic basis of the phenotypic diversity of ∼25 species of Takifugu that evolved within the last 5 My.