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Carlos Cordon-Cardo

Researcher at Icahn School of Medicine at Mount Sinai

Publications -  620
Citations -  91832

Carlos Cordon-Cardo is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Cancer & Prostate cancer. The author has an hindex of 144, co-authored 589 publications receiving 84862 citations. Previous affiliations of Carlos Cordon-Cardo include The Rogosin Institute & Erasmus University Rotterdam.

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p53 and RB: Simple Interesting Correlates or Tumor Markers of Critical Predictive Nature?

TL;DR: Chatterjee et al. as mentioned in this paper found that the number of altered proteins remained significantly correlated with both time to recurrence and overall survival in patients with bladder cancer, and that these proteins were independent predictors of both time-to-reaction and overall survivability.
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PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer.

TL;DR: Findings illustrate the critical role of cell–cell adhesion in the progression to aggressive prostate cancer, through regulation by the PI3K pathway.
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Immunopathologic analysis of human urinary bladder cancer. Characterization of two new antigens associated with low-grade superficial bladder tumors.

TL;DR: The normal human tissue distribution and tumor expression of two highly restricted tumor-associated antigens, detected by mouse monoclonal antibodies M344 and 19A211, which are primarily expressed on low-grade superficial urinary bladder tumors are characterized.
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TSPYL2 is an essential component of the REST/NRSF transcriptional complex for TGFβ signaling activation.

TL;DR: It is demonstrated that the TSPYL2/REST complex promotes TGFβ signaling by repressing the expression of genes, such as the proto-oncogene neurotrophic tyrosine kinase receptor C (TrkC), which provides insight into the role of REST as a tumor suppressor in epithelial tissues through the regulation of the TGF β pathway.