C
Carlos Cordon-Cardo
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 620
Citations - 91832
Carlos Cordon-Cardo is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Cancer & Prostate cancer. The author has an hindex of 144, co-authored 589 publications receiving 84862 citations. Previous affiliations of Carlos Cordon-Cardo include The Rogosin Institute & Erasmus University Rotterdam.
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Journal ArticleDOI
Genetic studies and molecular markers of bladder cancer.
TL;DR: The implementation of objective predictive assays to identify alterations in proto-oncogenes and tumor suppressor genes in clinical material will enhance the ability to assess tumor biological activities and to design effective treatment regimes.
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PPARγ agonists enhance ET-743–induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma
Elizabeth Charytonowicz,Melissa Terry,Katherine Coakley,Leonid Telis,Fabrizio Remotti,Carlos Cordon-Cardo,Robert N. Taub,Igor Matushansky +7 more
TL;DR: How clinical observations can lead to the generation of a mouse model that recapitulates human disease and may be used to develop rational treatment combinations, such as ET-743 plus PPARγ agonists, for the treatment of MRCLS are highlighted.
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Generation of Prostate Cancer Patient Derived Xenograft Models from Circulating Tumor Cells.
Estrelania Williams,Veronica Rodriguez-Bravo,Uma Chippada-Venkata,Janis De Ia Iglesia-Vicente,Yixuan Gong,Matthew D. Galsky,William Oh,Carlos Cordon-Cardo,Josep Domingo-Domenech +8 more
TL;DR: The generation of PDX models from CTCs provides a novel experimental model to be applied to prostate cancer research and is detailed in this manuscript.
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Modulation of apoptosis, proliferation, and p27 expression in a porcine coronary angioplasty model.
Mercè Roqué,Carlos Cordon-Cardo,Valentin Fuster,Ernane D. Reis,Marija Drobnjak,Juan J. Badimon +5 more
TL;DR: Coronary angioplasty induced a rapid apoptotic response, followed by a progressive increase in proliferation, later on, as p27 expression increased in the vessel wall, cell proliferation decreased, and modulation of cell cycle progression may be a useful therapeutic approach in the treatment of intimal hyperplasia after angiopLasty.
Journal ArticleDOI
Loss of Sirt1 Promotes Prostatic Intraepithelial Neoplasia, Reduces Mitophagy, and Delays Park2 Translocation to Mitochondria
Gabriele Di Sante,Timothy G. Pestell,Mathew C. Casimiro,Sara Bisetto,Michael J. Powell,Michael P. Lisanti,Carlos Cordon-Cardo,Mireia Castillo-Martin,Dennis M. Bonal,Valentina Debattisti,Ke Chen,Liping Wang,Xiaohong He,Michael W. McBurney,Richard G. Pestell +14 more
TL;DR: The NAD(+)-dependent inhibition of SOD2 activity and ROS by SIRT1 provides a gatekeeper function to reduce PARK2-mediated mitophagy and aberrant cell survival.