C
Carlos Cordon-Cardo
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 620
Citations - 91832
Carlos Cordon-Cardo is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Cancer & Prostate cancer. The author has an hindex of 144, co-authored 589 publications receiving 84862 citations. Previous affiliations of Carlos Cordon-Cardo include The Rogosin Institute & Erasmus University Rotterdam.
Papers
More filters
Journal ArticleDOI
Neuronal antinuclear antibody in sensory neuronopathy from lung cancer
TL;DR: An antinuclear antibody highly restricted to nuclei of neurons in two patients with subacute sensory neuronopathy complicating oat cell carcinoma of the lung is found.
Journal ArticleDOI
AKI in hospitalized patients with COVID-19
Lili Chan,Kumardeep Chaudhary,Aparna Saha,Kinsuk Chauhan,Akhil Vaid,Shan Zhao,Ishan Paranjpe,Sulaiman Somani,Felix Richter,Riccardo Miotto,Anuradha Lala,Arash Kia,Prem Timsina,Li Li,Robert Freeman,Rong Chen,Jagat Narula,Allan C. Just,Carol R. Horowitz,Zahi A. Fayad,Carlos Cordon-Cardo,Eric E. Schadt,Matthew A. Levin,David Reich,Valentin Fuster,Barbara Murphy,John Cijiang He,Alexander W. Charney,Erwin P. Bottinger,Benjamin S. Glicksberg,Steven G. Coca,Girish N. Nadkarni +31 more
TL;DR: This retrospective, observational study involved a review of data from electronic health records of patients aged ≥18 years with laboratory-confirmed COVID-19 admitted to the Mount Sinai Health System from February 27 to May 30, 2020 to describe the frequency of AKI and dialysis requirement, AKI recovery, and adjusted odds ratios with mortality.
Journal ArticleDOI
PML inhibits HIF-1α translation and neoangiogenesis through repression of mTOR
Rosa Bernardi,Ilhem Guernah,David K. Jin,Silvia Grisendi,Andrea Alimonti,Julie Teruya-Feldstein,Carlos Cordon-Cardo,M. Celeste Simon,M. Celeste Simon,Shahin Rafii,Pier Paolo Pandolfi +10 more
TL;DR: PML is identified as a critical inhibitor of neoangiogenesis in vivo, in both ischaemic and neoplastic conditions, through the control of protein translation and physically interacts with mTOR and negatively regulates its association with the small GTPase Rheb by favouring mTOR nuclear accumulation.
Journal ArticleDOI
Autocrine PDGFR signaling promotes mammary cancer metastasis
Martin Jechlinger,Andreas Sommer,Richard Moriggl,Peter Seither,Norbert Kraut,Paola Capodiecci,Michael J. Donovan,Carlos Cordon-Cardo,Hartmut Beug,Stefan Grünert +9 more
TL;DR: It is shown that metastatic potential of oncogenic mammary epithelial cells requires an autocrine PDGF/PDGFR loop, which is established as a consequence of TGF-beta-induced epithelial-mesenchymal transition (EMT), a faithful in vitro correlate of metastasis.
Journal ArticleDOI
Skp2 targeting suppresses tumorigenesis by Arf-p53- independent cellular senescence
Hui Kuan Lin,Zhenbang Chen,Zhenbang Chen,Zhenbang Chen,Guocan Wang,Caterina Nardella,Caterina Nardella,Szu Wei Lee,Chan Hsin Chan,Wei Lei Yang,Jing Wang,Ainara Egia,Keiichi I. Nakayama,Carlos Cordon-Cardo,Julie Teruya-Feldstein,Pier Paolo Pandolfi,Pier Paolo Pandolfi +16 more
TL;DR: It is shown that although Skp2 inactivation on its own does not induce cellular senescence, aberrant proto-oncogenic signals as well as inactivation of tumour suppressor genes do trigger a potent, tumour-suppressivesenescence response in mice and cells devoid of Skp1.