C
Carlos Cordon-Cardo
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 620
Citations - 91832
Carlos Cordon-Cardo is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Cancer & Prostate cancer. The author has an hindex of 144, co-authored 589 publications receiving 84862 citations. Previous affiliations of Carlos Cordon-Cardo include The Rogosin Institute & Erasmus University Rotterdam.
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Journal ArticleDOI
Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury
Sahra Bodo,Cecile G. Campagne,Cecile G. Campagne,Tin Htwe Thin,Tin Htwe Thin,Daniel S. Higginson,H. Alberto Vargas,Guoqiang Hua,Guoqiang Hua,John D. Fuller,Ellen Ackerstaff,James A. Russell,Zhigang Zhang,Stefan Klingler,HyungJoon Cho,HyungJoon Cho,Matthew Kaag,Yousef Mazaheri,Andreas Rimner,Katia Manova-Todorova,Boris Epel,Joan Zatcky,C.R. Cleary,Shyam Rao,Yoshiya Yamada,Michael J. Zelefsky,Howard J. Halpern,Jason A. Koutcher,Carlos Cordon-Cardo,Carlo Greco,Adriana Haimovitz-Friedman,Evis Sala,Evis Sala,Simon N. Powell,Richard Kolesnick,Zvi Fuks,Zvi Fuks +36 more
TL;DR: It is reported that single-dose radiotherapy (SDRT), a disruptive technique that ablates more than 90% of human cancers, operates a distinct dual-target mechanism, linking acid sphingomyelinase–mediated (ASMase-mediated) microvascular perfusion defects to DNA unrepair in tumor cells to confer tumor cell lethality.
Journal Article
Machine Learning to Predict Mortality and Critical Events in COVID-19 Positive New York City Patients: A Cohort Study
Akhil Vaid,Sulaiman Somani,Adam Russak,J. K. De Freitas,Fayzan Chaudhry,Ishan Paranjpe,Kipp W. Johnson,Shawn Lee,Riccardo Miotto,Felix Richter,Shan Zhao,Noam D. Beckmann,Nidhi Naik,Arash Kia,Prem Timsina,Anuradha Lala,Manish Paranjpe,Eddye Golden,Matteo Danieletto,Manbir Singh,Dara Meyer,Paul F. O'Reilly,Laura M. Huckins,Patricia Kovatch,Joseph Finkelstein,Robert Freeman,Edgar Argulian,Andrew Kasarskis,Bethany Percha,Judith A. Aberg,Emilia Bagiella,Carol R. Horowitz,Barbara Murphy,Eric J. Nestler,Eric E. Schadt,Judy H. Cho,Carlos Cordon-Cardo,V Fuster,Dennis S. Charney,David Reich,Erwin P. Bottinger,Matthew A. Levin,Jagat Narula,Zahi A. Fayad,Allan C Just,Alexander W Charney,Girish N. Nadkarni,Benjamin S. Glicksberg +47 more
TL;DR: Electronic Health Records from COVID-19 positive hospitalized patients admitted to the Mount Sinai Health System in New York City are analyzed to establish model interpretability to identify and rank variables that drive model predictions and identify at-risk patients.
Journal Article
Intranuclear compartmentalization of cyclin E during the cell cycle: disruption of the nucleoplasm-nucleolar shuttling of cyclin E in bladder cancer.
Gloria Juan,Carlos Cordon-Cardo +1 more
TL;DR: Observations suggest that the nucleolus mediates a cyclin E "shuttling" between the nucleus and the cytoplasm that is probably involved in its regulation and that this mechanism could be disrupted in bladder cancer.
Journal ArticleDOI
KISS1 methylation and expression as tumor stratification biomarkers and clinical outcome prognosticators for bladder cancer patients.
Virginia Cebrian,Marta Fierro,Esteban Orenes-Piñero,Laura Grau,Patricia Moya,Thorsten Ecke,M A Alvarez,Marta Gil,Ferran Algaba,Joaquin Bellmunt,Carlos Cordon-Cardo,James W.F. Catto,Antonio Lopez-Beltran,Marta Sanchez-Carbayo +13 more
TL;DR: In this paper, the authors evaluated the biological influence of KISS1 methylation on its expression and clinical relevance in bladder cancer and found that KISS 1 hypermethylation was associated with low gene expression, being restored by demethylating azacytidine.
Journal ArticleDOI
Expression of p63 in diffuse large B-cell lymphoma.
Cyrus V. Hedvat,Julie Teruya-Feldstein,Pere Puig,Paola Capodieci,Maria E. Dudas,Natalie Pica,Jing Qin,Carlos Cordon-Cardo,Charles J. Di Como +8 more
TL;DR: Even though in univariate analysis p63 expression did not correlate with overall survival, the association of p63 with increased proliferative index suggests its involvement in DLBCL tumor progression.