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Carolyn Hernandez
Researcher at University of California, San Diego
Publications - 20
Citations - 2145
Carolyn Hernandez is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Nonalcoholic fatty liver disease & Fatty liver. The author has an hindex of 15, co-authored 20 publications receiving 1566 citations.
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Journal ArticleDOI
Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients with Biopsy-proven Nonalcoholic Fatty Liver Disease
Charlie C. Park,Phirum Nguyen,Carolyn Hernandez,Ricki Bettencourt,Kimberly Ramirez,Lynda Fortney,Jonathan Hooker,Ethan Z. Sy,Michael T. Savides,Mosab H. Alquiraish,Mark A. Valasek,Emily Rizo,Lisa Richards,David A. Brenner,Claude B. Sirlin,Rohit Loomba +15 more
TL;DR: In a prospective, cross-sectional study of more than 100 patients, MRE is found to be more accurate than TE in identification of liver fibrosis (stage 1 or more), using biopsy analysis as the standard and MRI-PDFF is more accurate in detecting all grades of steatosis in patients with NAFLD.
Journal ArticleDOI
Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study
Rohit Loomba,Nicholas J. Schork,Chi-Hua Chen,Ricki Bettencourt,Ana Bhatt,Brandon Ang,Phirum Nguyen,Carolyn Hernandez,Lisa Richards,Joanie Salotti,Steven C. Lin,Ekihiro Seki,Karen E. Nelson,Claude B. Sirlin,David A. Brenner +14 more
TL;DR: A cross-sectional analysis of a cohort of well-characterized twins residing in Southern California provides evidence that hepatic steatosis and hepatic fibrosis are heritable traits.
Journal ArticleDOI
Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial.
Jeffrey Cui,Len Philo,Phirum Nguyen,Heather Hofflich,Carolyn Hernandez,Ricki Bettencourt,Lisa Richards,Joanie Salotti,Archana Bhatt,Jonathan Hooker,William Haufe,Catherine A. Hooker,David A. Brenner,Claude B. Sirlin,Rohit Loomba +14 more
TL;DR: Sitagliptin was safe but not better than placebo in reducing liver fat in prediabetic or diabetic patients with NAFLD and demonstrates that non-invasive magnetic resonance imaging techniques can be used to assess treatment response in non-alcoholic fatty liver disease clinical trials.
Journal ArticleDOI
Optimal threshold of controlled attenuation parameter with MRI-PDFF as the gold standard for the detection of hepatic steatosis
Cyrielle Caussy,Cyrielle Caussy,Mosab H. Alquiraish,Phirum Nguyen,Carolyn Hernandez,Sandra Cepin,Lynda Fortney,Veeral Ajmera,Ricki Bettencourt,Summer Collier,Jonathan Hooker,Ethan Z. Sy,Emily Rizo,Lisa Richards,Claude B. Sirlin,Rohit Loomba +15 more
TL;DR: The diagnostic accuracy of CAP for the detection of hepatic steatosis is more reliable when the IQR of CAP is <30 dB/m, and these data have implications for the clinical use of CAP in the assessment of NAFLD.
Journal ArticleDOI
Magnetic resonance elastography is superior to acoustic radiation force impulse for the Diagnosis of fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease: A prospective study
Jeffrey Cui,Elhamy Heba,Carolyn Hernandez,William Haufe,Jonathan Hooker,Michael P. Andre,Mark A. Valasek,H. Aryafar,Claude B. Sirlin,Rohit Loomba +9 more
TL;DR: MRE is more accurate than ARFI for diagnosing any fibrosis in NAFLD patients, especially those who are obese, and differences decreased as the cutoff points (fibrosis stages) increased.