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Phirum Nguyen
Researcher at University of California, San Diego
Publications - 20
Citations - 2111
Phirum Nguyen is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Nonalcoholic fatty liver disease & Fatty liver. The author has an hindex of 14, co-authored 20 publications receiving 1597 citations.
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Journal ArticleDOI
Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients with Biopsy-proven Nonalcoholic Fatty Liver Disease
Charlie C. Park,Phirum Nguyen,Carolyn Hernandez,Ricki Bettencourt,Kimberly Ramirez,Lynda Fortney,Jonathan Hooker,Ethan Z. Sy,Michael T. Savides,Mosab H. Alquiraish,Mark A. Valasek,Emily Rizo,Lisa Richards,David A. Brenner,Claude B. Sirlin,Rohit Loomba +15 more
TL;DR: In a prospective, cross-sectional study of more than 100 patients, MRE is found to be more accurate than TE in identification of liver fibrosis (stage 1 or more), using biopsy analysis as the standard and MRI-PDFF is more accurate in detecting all grades of steatosis in patients with NAFLD.
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Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial).
Rohit Loomba,Claude B. Sirlin,Brandon Ang,Ricki Bettencourt,Rashmi Jain,Joanie Salotti,Linda Soaft,Jonathan Hooker,Yuko Kono,Archana Bhatt,Laura Hernandez,Phirum Nguyen,Mazen Noureddin,William Haufe,Catherine A. Hooker,Meng Yin,Richard L. Ehman,Grace Y. Lin,Mark A. Valasek,David A. Brenner,Lisa Richards +20 more
TL;DR: This trial demonstrates the application of colocalization of MRI‐PDFF‐derived fat maps and magnetic resonance elastography‐derived stiffness maps of the liver before and after treatment to noninvasively assess treatment response in NASH.
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Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study
Rohit Loomba,Nicholas J. Schork,Chi-Hua Chen,Ricki Bettencourt,Ana Bhatt,Brandon Ang,Phirum Nguyen,Carolyn Hernandez,Lisa Richards,Joanie Salotti,Steven C. Lin,Ekihiro Seki,Karen E. Nelson,Claude B. Sirlin,David A. Brenner +14 more
TL;DR: A cross-sectional analysis of a cohort of well-characterized twins residing in Southern California provides evidence that hepatic steatosis and hepatic fibrosis are heritable traits.
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Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial.
Jeffrey Cui,Len Philo,Phirum Nguyen,Heather Hofflich,Carolyn Hernandez,Ricki Bettencourt,Lisa Richards,Joanie Salotti,Archana Bhatt,Jonathan Hooker,William Haufe,Catherine A. Hooker,David A. Brenner,Claude B. Sirlin,Rohit Loomba +14 more
TL;DR: Sitagliptin was safe but not better than placebo in reducing liver fat in prediabetic or diabetic patients with NAFLD and demonstrates that non-invasive magnetic resonance imaging techniques can be used to assess treatment response in non-alcoholic fatty liver disease clinical trials.
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Optimal threshold of controlled attenuation parameter with MRI-PDFF as the gold standard for the detection of hepatic steatosis
Cyrielle Caussy,Cyrielle Caussy,Mosab H. Alquiraish,Phirum Nguyen,Carolyn Hernandez,Sandra Cepin,Lynda Fortney,Veeral Ajmera,Ricki Bettencourt,Summer Collier,Jonathan Hooker,Ethan Z. Sy,Emily Rizo,Lisa Richards,Claude B. Sirlin,Rohit Loomba +15 more
TL;DR: The diagnostic accuracy of CAP for the detection of hepatic steatosis is more reliable when the IQR of CAP is <30 dB/m, and these data have implications for the clinical use of CAP in the assessment of NAFLD.