C
Cecile Loison
Publications - 10
Citations - 1462
Cecile Loison is an academic researcher. The author has contributed to research in topics: Receptor & Ligand (biochemistry). The author has an hindex of 3, co-authored 10 publications receiving 1239 citations.
Papers
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Journal ArticleDOI
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.
Emmanuel Le Poul,Cecile Loison,Sofie Struyf,Jean-Yves Springael,Vincent Lannoy,Marie-Eve Decobecq,Stéphane Brézillon,Vincent Dupriez,Gilbert Vassart,Jozef Van Damme,Marc Parmentier,Michel Detheux +11 more
TL;DR: The pharmacology of GPR43 matches indeed the effects of SCFAs on neutrophils, in terms of intracellular Ca2+ release and chemotaxis, and might constitute a target allowing us to modulate immune responses in these pathological situations.
Journal ArticleDOI
Identification and characterization of an endogenous chemotactic ligand specific for FPRL2.
Isabelle Migeotte,Elena Riboldi,Jean-Denis Franssen,Françoise Grégoire,Cecile Loison,Valérie Wittamer,Michel Detheux,Patrick Robberecht,Sabine Costagliola,Gilbert Vassart,Silvano Sozzani,Silvano Sozzani,Marc Parmentier,David Communi +13 more
TL;DR: F2L appears as a new natural chemoattractant peptide for DCs and monocytes, and the first potent and specific agonist of FPRL2, the third member of this structural family of chemoATTractant receptors.
Patent
Compositions and methods comprising a ligand of chemerinR
Valeria Wittamer,J. F. Mirjolet,Isabelle Migeotte,David Communi,Alberto Mantovani,Silvano Sozzani,Marisa Vulcano,Jean-Denis Franseen,Stéphane Brézillon,Michel Detheux,Gilbert Vassart,Marc Parmentier,Emmanuel Le Poul,Cecile Loison,Frederic Ooms +14 more
TL;DR: In this paper, a G-protein coupled receptor and a novel ligand were proposed for the diagnosis and treatment of a disease or disorder related to the dysregulation of Gprotein-coupled receptor signaling.
Patent
Functional antibodies that specifically bind to the Chemerin receptor
Valérie Wittamer,Jean-Francois Mirjolet,Isabelle Migeotte,David Communi,Alberto Mantovani,Silvano Sozzani,Marisa Vulcano,Jean-Denis Franssen,Stéphane Brézillon,Michel Detheux,Gilbert Vassart,Marc Parmentier,Emmanuel LePoul,Cecile Loison,Frederic Ooms +14 more
TL;DR: In this article, a G-protein coupled receptor and a novel ligand were proposed for the diagnosis and treatment of a disease or disorder related to the dysregulation of Gprotein-coupled receptor signaling.
Patent
Methods of making an antibody that binds a chemerin polypeptide
Valérie Wittamer,Jean-Francois Mirjolet,Isabelle Migeotte,David Communi,Alberto Mantovani,Silvano Sozzani,Marisa Vulcano,Jean-Denis Franssen,Stéphane Brézillon,Michel Detheux,Gilbert Vassart,Marc Parmentier,Emmanuel Le Poul,Cecile Loison,Frederic Ooms +14 more
TL;DR: In this article, a G-protein coupled receptor and a novel ligand were proposed for the identification of candidate compounds which modulate the activity of the G-Paired receptor, as well as assays useful for the diagnosis and treatment of a disease or disorder related to the dysregulation of G protein coupled receptor signaling.