Chao Zhang

TL;DR: The concept of a light-dependent activation barrier is introduced to account for the effect of light illumination on electronic and thermal excitations in a single unified picture and provides insight into the specific role of hot carriers in plasmon-mediated photochemistry, which is critically important for designing energy-efficient plAsmonic photocatalysts.

TL;DR: The underlying biology of BRAF, the technology used to identify vemurafenib and its clinical development milestones, along with future prospects based on lessons learned during its development are described.

TL;DR: It is demonstrated that permanently cross-linked hydrogels can be engineered to exhibit self-healing in an aqueous environment, and how secondary interactions could be harnessed to introduce new functions to chemically cross- linked polymeric systems is revealed.

TL;DR: It is shown that oligomerization is central to Ire1 function and is an intrinsic attribute of its cytosolic domains in complex with a kinase inhibitor that acts as a potent activator of the Ire1 RNase.

TL;DR: This review presents a systematic review on the fabrication routes of ASCs followed by an overview of some new and effective characterization methods to precisely probe the atomic structure and discusses the challenges and opportunities on the further development of more selective, active, stable and less expensive ASCs.