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Charles J. Arntzen

Researcher at Arizona State University

Publications -  187
Citations -  18206

Charles J. Arntzen is an academic researcher from Arizona State University. The author has contributed to research in topics: Photosystem II & Photosystem I. The author has an hindex of 71, co-authored 186 publications receiving 17776 citations. Previous affiliations of Charles J. Arntzen include Cornell University & University of Illinois at Urbana–Champaign.

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Expression of hepatitis B surface antigen in transgenic plants.

TL;DR: Because the HBsAg produced in transgenic plants is antigenically and physically similar to theHBsAg particles derived from human serum and recombinant yeast, which are used as vaccines, it is concluded that transgenic Plants hold promise as low-cost vaccine production systems.
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Chloroplast protein phosphorylation couples plastoquinone redox state to distribution of excitation energy between photosystems

TL;DR: In photosynthetic membranes isolated from pea leaves, the redox state of the plastoquinone pool controls both the level of phosphorylation of the chloroplast light-harvesting pigment–protein complex (LHC) and distribution of absorbed excitation energy between the two photosystems.
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Oral immunization with a recombinant bacterial antigen produced in transgenic plants

TL;DR: Mice immunized by gavage produced serum and gut mucosal anti-LT-B immunoglobulins that neutralized the enterotoxin in cell protection assays and feeding fresh transgenic potato tubers caused oral immunization.
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Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato.

TL;DR: The present study was conducted as a proof of principle to determine if humans would also develop a serum and/or mucosal immune response to an antigen delivered in an uncooked foodstuff.
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Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice.

TL;DR: The results indicate the potential usefulness of plants for production and delivery of edible vaccines, an appropriate technology for developing countries where vaccines are urgently needed.