C
Chiara Cerletti
Researcher at The Catholic University of America
Publications - 240
Citations - 7871
Chiara Cerletti is an academic researcher from The Catholic University of America. The author has contributed to research in topics: Platelet & Population. The author has an hindex of 45, co-authored 208 publications receiving 6845 citations. Previous affiliations of Chiara Cerletti include University of Münster & Mario Negri Institute for Pharmacological Research.
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Journal ArticleDOI
Recommendations for the standardization of light transmission aggregometry : a consensus of the working party from the platelet physiology subcommittee of SSC/ISTH
Marco Cattaneo,Chiara Cerletti,Paul Harrison,Catherine P.M. Hayward,Dermot Kenny,Diane J. Nugent,Paquita Nurden,A. K. Rao,Alvin H. Schmaier,Steve P. Watson,Federico Lussana,Mariateresa Pugliano,Alan D. Michelson +12 more
TL;DR: The Platelet Physiology Subcommittee of the Scientific and Standardization Committee (SSC) of the International Society on Thrombosis and Haemostasis formed a working party of experts with the aim of producing a series of consensus recommendations for standardizing LTA, which formed the basis of a consensus document, which is the subject of the present report.
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Platelet/Polymorphonuclear Leukocyte Interaction: P-Selectin Triggers Protein-Tyrosine Phosphorylation–Dependent CD11b/CD18 Adhesion: Role of PSGL-1 as a Signaling Molecule
Virgilio Evangelista,Virgilio Evangelista,S. Manarini,S. Manarini,Rita Sideri,Rita Sideri,Serenella Rotondo,Serenella Rotondo,Nicola Martelli,Nicola Martelli,Antonio Piccoli,Antonio Piccoli,Licia Totani,Licia Totani,P Piccardoni,P Piccardoni,Dietmar Vestweber,Dietmar Vestweber,Giovanni de Gaetano,Giovanni de Gaetano,Chiara Cerletti,Chiara Cerletti +21 more
TL;DR: This study shows that binding of P-selectin to PSGL-1 triggers tyrosine kinase–dependent mechanisms that lead to CD11b/CD18 activation in PMN, and engagement of PS GL-1 with a nonadhesion blocking antibody triggered β2-integrin–dependent genistein-sensitive aggregation as well as tyrosinesine phosphorylation in PMn.
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Aspirin resistance: position paper of the Working Group on Aspirin Resistance
Allan D. Michelson,Marco Cattaneo,John W. Eikelboom,Paul A. Gurbel,Kandice Kottke-Marchant,Thomas J. Kunicki,Fabio M. Pulcinelli,Chiara Cerletti,A. K. Rao +8 more
TL;DR: This work presents a meta-analysis of Platelet Function Studies and Hemostasis in relation to Thrombosis and Haemostasis that shows clear trends in prognosis and in particular in cases of high-risk individuals, where the prognosis for survival is poorer for those with high levels of Aspirin resistance.
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Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera
Anna Falanga,Marina Marchetti,Virgilio Evangelista,Alfonso Vignoli,Marina Licini,Mara Balicco,Stefano Manarini,Guido Finazzi,Chiara Cerletti,Tiziano Barbui +9 more
TL;DR: For the first time, data show that in ET and PV, 2 hematologic conditions that place patients at increased risk for thrombosis, an in vivo leukocyte activation occurs and is associated with laboratory signs of endothelium and coagulation system activation.
Journal ArticleDOI
Effect of trans-resveratrol, a natural polyphenolic compound, on human polymorphonuclear leukocyte function
Serenella Rotondo,G. Rajtar,Stefano Manarini,A. Celardo,Domenico Rotilio,Giovanni de Gaetano,Virgilio Evangelista,Chiara Cerletti +7 more
TL;DR: Results indicate that trans‐resveratrol interferes with the release of inflammatory mediators by activated PMN and down‐regulates adhesion‐dependent thrombogenic PMN functions, which may provide some biological plausibility to the protective effect of red wine consumption against CHD.