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Chih Wei Chien
Researcher at Carnegie Institution for Science
Publications - 15
Citations - 825
Chih Wei Chien is an academic researcher from Carnegie Institution for Science. The author has contributed to research in topics: Proteome & Arabidopsis. The author has an hindex of 13, co-authored 15 publications receiving 716 citations. Previous affiliations of Chih Wei Chien include Chang Gung University & National Tsing Hua University.
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Journal ArticleDOI
Concerted genomic targeting of H3K27 demethylase REF6 and chromatin-remodeling ATPase BRM in Arabidopsis
Chenlong Li,Chenlong Li,Lianfeng Gu,Lianfeng Gu,Lianfeng Gu,Lei Gao,Chen Chen,Chen Chen,Chuang-Qi Wei,Chuang-Qi Wei,Qi Qiu,Chih Wei Chien,Suikang Wang,Suikang Wang,Lihua Jiang,Lian-Feng Ai,Chia-Yang Chen,Songguang Yang,Vi Nguyen,Yanhua Qi,Michael Snyder,Alma L. Burlingame,Susanne E. Kohalmi,Shangzhi Huang,Xiaofeng Cao,Zhi-Yong Wang,Keqiang Wu,Xuemei Chen,Yuhai Cui,Yuhai Cui +29 more
TL;DR: This work identifies a new genomic targeting mechanism for an H3K27 demethylase and demonstrates its key role in recruiting the BRM chromatin remodeler.
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A Multiplexed Quantitative Strategy for Membrane Proteomics Opportunities for Mining Therapeutic Targets for Autosomal Dominant Polycystic Kidney Disease
TL;DR: This method demonstrates how comparative membrane proteomics can provide insight into the molecular mechanisms underlying ADPKD and the identification of potential drug targets, which may lead to new therapeutic opportunities to prevent or retard the disease.
Journal ArticleDOI
A fluorescent carbazole derivative: high sensitivity for quadruplex DNA.
Cheng-Chung Chang,Jin-Yi Wu,Chih Wei Chien,Wei-Sung Wu,Heng Liu,Chi-Chih Kang,Liang-Jye Yu,Ta-Chau Chang +7 more
TL;DR: The fluorescence intensity of the 3,6-bis(1-methyl-4-vinylpyridium)carbazole diiodide molecule increases from 1 to almost 2 orders of magnitude upon interacting with various DNAs and can be used to discriminate between duplex and quadruplex DNAs.
Journal ArticleDOI
The Arabidopsis B-box protein BZS1/BBX20 interacts with HY5 and mediates strigolactone regulation of photomorphogenesis.
Chuang-Qi Wei,Chih Wei Chien,Lian-Feng Ai,Jun Zhao,Zhenzhen Zhang,Kathy H. Li,Alma L. Burlingame,Yu Sun,Zhi-Yong Wang +8 more
TL;DR: It is demonstrated that BZS1 interacts with HY5 and plays a central role in integrating light and multiple hormone signals for photomorphogenesis in Arabidopsis.
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An informatics-assisted label-free approach for personalized tissue membrane proteomics: case study on colorectal cancer
Chia Li Han,Jinn Shiun Chen,Jinn Shiun Chen,Err-Cheng Chan,Chien Peng Wu,Kun-Hsing Yu,Kuei Tien Chen,Chih-Chiang Tsou,Chia-Feng Tsai,Chih Wei Chien,Yung Bin Kuo,Pei-Yi Lin,Jau-Song Yu,Chuen Hsueh,Chuen Hsueh,Min Chi Chen,Chung Chuan Chan,Yu-Sun Chang,Yu-Ju Chen,Yu-Ju Chen +19 more
TL;DR: This study demonstrated a sensitive, label-free strategy for differential analysis of tissue membrane proteome, which may provide a roadmap for the subsequent identification of molecular target candidates of multiple cancer types.