C
Christelle Piperoglou
Researcher at Aix-Marseille University
Publications - 28
Citations - 1794
Christelle Piperoglou is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Innate lymphoid cell & Medicine. The author has an hindex of 13, co-authored 24 publications receiving 1242 citations.
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Journal ArticleDOI
Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis.
Julien Carvelli,Olivier Demaria,Frédéric Vély,Luciana Batista,Nassima Chouaki Benmansour,Joanna Fares,Sabrina Carpentier,Marie-Laure Thibult,Ariane Morel,Romain Remark,Pascale Andre,Agnès Represa,Christelle Piperoglou,Pierre Yves Cordier,Erwan Le Dault,Christophe Guervilly,Pierre Simeone,Marc Gainnier,Yannis Morel,Mikael Ebbo,Nicolas Schleinitz,Eric Vivier +21 more
TL;DR: Results suggest that blockade of the C5a–C5aR1 axis could be used to limit the infiltration of myeloid cells in damaged organs and prevent the excessive lung inflammation and endothelialitis that are associated with acute respiratory distress syndrome in patients with COVID-19.
Journal ArticleDOI
High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice
Adeline Crinier,Pierre Milpied,Bertrand Escalière,Christelle Piperoglou,Justine Galluso,Anaïs Balsamo,Lionel Spinelli,Inaki Cervera-Marzal,Mikael Ebbo,Mathilde J. H. Girard-Madoux,Sébastien Jaeger,Emilie Bollon,Sami Hamed,Jean Hardwigsen,Sophie Ugolini,Frédéric Vély,Emilie Narni-Mancinelli,Eric Vivier +17 more
TL;DR: Using high‐throughput single‐cell RNA‐seq, Crinier et al. provide conserved tissue‐specific gene signatures of NK cells from spleen and blood and identified two major NK cell subsets transcriptionally similar across organs and species.
Journal ArticleDOI
Evidence of innate lymphoid cell redundancy in humans
Frédéric Vély,Vincent Barlogis,Blandine Vallentin,Bénédicte Neven,Christelle Piperoglou,Mikael Ebbo,Thibaut Perchet,Thibaut Perchet,Maxime Petit,Maxime Petit,Nadia Yessaad,Fabien Touzot,Fabien Touzot,Julie Bruneau,Julie Bruneau,Nizar Mahlaoui,Nicolas Zucchini,Catherine Farnarier,Gérard Michel,Despina Moshous,Stéphane Blanche,Arnaud Dujardin,Hergen Spits,Jörg H W Distler,Andreas Ramming,Capucine Picard,Rachel Golub,Rachel Golub,Alain Fischer,Eric Vivier +29 more
TL;DR: The authors investigated the presence of ILCs in a cohort of patients with severe combined immunodeficiency (SCID) and found that ILC subsets were absent in patients with SCID who had mutation of the gene encoding the common γ-chain cytokine receptor subunit IL-2Rγ or the tyrosine kinase JAK3.
Posted Content
Evidence of innate lymphoid cell redundancy in humans (vol 17, pg 1291, ă 2016)
Frédéric Vély,Vincent Barlogis,Blandine Vallentin,Bénédicte Neven,Christelle Piperoglou,Mikael Ebbo,Thibaut Perchet,Maxime Petit,Nadia Yessaad,Fabien Touzot,Julie Bruneau,Nizar Mahlaoui,Nicolas Zucchini,Catherine Farnarier,Gérard Michel,Despina Moshous,Stéphane Blanche,Arnaud Dujardin,Hergen Spits,Joerg H. W. Distler,Andreas Ramming,Capucine Picard,Rachel Golub,Alain Fischer,Eric Vivier +24 more
TL;DR: Selective ILC deficiency in humans is reported and it is shown that ILCs might be dispensable in natural conditions, if T cells are present and B cell function is preserved.
Journal ArticleDOI
Induction of B7-H6, a ligand for the natural killer cell–activating receptor NKp30, in inflammatory conditions
Jessica Matta,Jessica Matta,Jessica Matta,Myriam Baratin,Myriam Baratin,Myriam Baratin,Laurent Chiche,Jean-Marie Forel,Céline Cognet,G. Thomas,Catherine Farnarier,Christelle Piperoglou,Laurent Papazian,Damien Chaussabel,Sophie Ugolini,Sophie Ugolini,Sophie Ugolini,Frédéric Vély,Eric Vivier +18 more
TL;DR: Findings reveal that B7-H6 is not only implicated in tumor immunosurveillance but also participates in the inflammatory response in infectious conditions.