Myriam Baratin

TL;DR: Although NK cells might appear to be redundant in several conditions of immune challenge in humans, NK cell manipulation seems to hold promise in efforts to improve hematopoietic and solid organ transplantation, promote antitumor immunotherapy and control inflammatory and autoimmune disorders.

TL;DR: The identification of a tumor cell surface molecule that binds NKp30, a human receptor which triggers antitumor NK cell cytotoxicity and cytokine secretion is reported and this previously unannotated gene belongs to the B7 family and was designated B7-H6, emphasizing that the expression of stress-induced self-molecules associated with cell transformation serves as a mode of cell recognition in innate immunity.

TL;DR: It is found that S1P5 was required for the mobilization of NK cells to inflamed organs and the possibility that NK cell trafficking may be manipulated by therapies specifically targeting S1p5 is raised.

TL;DR: It is shown here that macrophages are mandatory for NK cell IFN-gamma secretion in response to erythrocytes infected with Plasmodium falciparum, a causative agent of human malaria.

TL;DR: Findings reveal that B7-H6 is not only implicated in tumor immunosurveillance but also participates in the inflammatory response in infectious conditions.